Macromelia, pronounced /mækroʊˈmiːliə/, is a medical term used to describe the abnormal enlargement of limbs or extremities. The word is derived from the Greek roots "macro" meaning large and "melos" meaning limb, which are reflected in the spelling of the word. The "c" in "macro" indicates a hard "k" sound, while the emphasis falls on the second syllable "me" with a long "e" sound. The final syllable "lia" is pronounced with a schwa sound, as in "uh".
Macromelia is a medical term that refers to an abnormal and excessive enlargement of one or more limbs in relation to the rest of the body. The term combines the prefix "macro-" meaning large or big, and the suffix "-melia" meaning limbs. Macromelia can be bilateral, affecting both limbs, or unilateral, affecting only one limb. It is a rare condition, often associated with certain genetic disorders or developmental abnormalities.
The excessive growth or enlargement seen in macromelia can occur in various tissues, such as bones, muscles, or soft tissues. This can lead to a significant size discrepancy between the affected limb(s) and the rest of the body. The condition usually manifests itself early in life, during infancy or childhood, and may progressively worsen over time.
The specific causes of macromelia can vary, but they often involve genetic mutations or alterations that disrupt normal growth and development processes. In some cases, it may be a result of overgrowth syndromes or other conditions affecting the skeletal or muscular systems.
Treatment options for macromelia depend on the underlying cause and the severity of the condition. They may include medical management, physical therapy, or surgical interventions to correct the size discrepancy and improve functionality.
Megalomelia, abnormal size of one or more of the extremities.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
The word macromelia is derived from the combination of two Greek roots: macro meaning large or long and melos meaning limb or extremity. When combined, macromelia literally translates to enlarged limbs or long extremities.