MACROCYCLIC POLYKETIDE Meaning and
Definition
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A macrocyclic polyketide refers to a type of organic compound that is derived from the condensation of several smaller units called ketides. These ketides are synthesized through a complex set of biochemical reactions known as polyketide synthesis, which occur in various natural sources such as bacteria, fungi, and plants.
Macrocyclic polyketides are characterized by their large, cyclic structure composed of multiple carbon atoms joined together in a ring-like arrangement. The cyclic structure often contains various functional groups, including hydroxyls, ketones, esters, and sometimes amino sugars. These functional groups contribute to the compound's diverse chemical properties and ultimately determine its biological activities.
Macrocyclic polyketides are known for their significant role in the field of medicine, as many of them possess pharmacological properties that make them highly valuable in drug discovery and development. Their structural complexity often allows them to interact with specific biological targets, such as enzymes or cell receptors, exerting therapeutic effects in the treatment of various diseases. Examples of macrocyclic polyketides include erythromycin, rapamycin, and tetracycline, which have been widely used as antibiotics or immunosuppressants.
Furthermore, the structural diversity exhibited by macrocyclic polyketides has attracted significant interest among chemists, who frequently exploit their intricate frameworks as inspiration for developing new synthetic methodologies or designing novel therapeutics.
Common Misspellings for MACROCYCLIC POLYKETIDE
- nacrocyclic polyketide
- kacrocyclic polyketide
- jacrocyclic polyketide
- mzcrocyclic polyketide
- mscrocyclic polyketide
- mwcrocyclic polyketide
- mqcrocyclic polyketide
- maxrocyclic polyketide
- mavrocyclic polyketide
- mafrocyclic polyketide
- madrocyclic polyketide
- maceocyclic polyketide
- macdocyclic polyketide
- macfocyclic polyketide
- mactocyclic polyketide
- mac5ocyclic polyketide
- mac4ocyclic polyketide
- macricyclic polyketide
- macrkcyclic polyketide
- macrlcyclic polyketide
Etymology of MACROCYCLIC POLYKETIDE
The word "macrocyclic polyketide" is a scientific term and its etymology can be understood by breaking it down into its constituent parts:
1. Macrocyclic: "Macrocyclic" is derived from the combination of the Greek prefix "macro-" meaning large or long and the root word "cycle" which refers to a circular or ring-like structure. In this context, "macrocyclic" refers to a molecule that contains a large ring structure.
2. Polyketide: "Polyketide" is a compound formed by the linking of multiple ketide units. The term is derived from the combination of the Greek prefix "poly-" meaning many and "ketide" which refers to an organic compound containing a carbonyl group (C=O) attached to two carbon atoms.
Therefore, "macrocyclic polyketide" refers to a large ring-like structure formed by the linking of multiple ketide units.
