M Aminosalicylic Acid, also known as para-aminosalicylic acid (PAS), is a chemical compound that belongs to the class of aminosalicylates. It is utilized primarily as a second-line drug for the treatment of tuberculosis, a bacterial infection caused by Mycobacterium tuberculosis.
The chemical structure of m aminosalicylic acid consists of an aminobenzoic acid molecule with a para-aminophenol group attached to it. It is available in the form of white, odorless, crystalline powder that is insoluble in water, but dissolves in dilute alkali solutions.
M Aminosalicylic Acid is chosen for tuberculosis treatment, particularly for drug-resistant cases or when resistance to first-line drugs like isoniazid and rifampicin is encountered. It functions by inhibiting the synthesis of mycolic acids, which are vital constituents of the Mycobacterium tuberculosis cell wall.
The drug is typically administered orally in tablet or capsule form. It is generally suggested to consume m aminosalicylic acid with a high-protein meal, as it improves its absorption. The dosage and duration of treatment are determined by the severity of the infection and the patient's individual characteristics.
However, it is crucial to be cautious when using m aminosalicylic acid as it may cause adverse effects like nausea, vomiting, diarrhea, abdominal pain, headache, and possible liver problems. Regular monitoring of liver function is necessary during treatment. If symptoms worsen or persist, it is important to consult a healthcare professional for proper guidance.
