LUTROPIN RECEPTORS Meaning and
Definition
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Lutropin receptors, also known as luteinizing hormone receptors (LHRs), are specialized proteins found on the surface of certain cells in the body. They are part of the G protein-coupled receptor family and play a crucial role in the regulation of reproductive functions. Specifically, lutropin receptors are primarily found in the ovary and testes and are essential for the normal functioning of these organs.
The main ligand that binds to lutropin receptors is luteinizing hormone (LH), a hormone released by the pituitary gland. LH stimulates the production and release of sex hormones such as estrogen and progesterone in females, and testosterone in males. In females, lutropin receptors present on the ovarian follicles are vital for follicular development, ovulation, and the formation of the corpus luteum. In males, these receptors in the Leydig cells of the testes are necessary for testosterone synthesis.
Lutropin receptors are transmembrane proteins consisting of an extracellular domain, a seven-pass transmembrane domain, and an intracellular domain. Upon binding of LH to the extracellular domain, the receptor undergoes conformational changes that activate the G protein system, leading to the initiation of various intracellular signaling cascades.
Mutations or abnormalities in lutropin receptors can lead to reproductive disorders and infertility. For example, certain genetic conditions, like familial male-limited precocious puberty, are caused by activating mutations in lutropin receptors, resulting in the early onset of puberty in boys. In contrast, defects or deficiency in lutropin receptors may cause conditions such as hypogonadism or anovulation.
Common Misspellings for LUTROPIN RECEPTORS
- kutropin receptors
- putropin receptors
- outropin receptors
- lytropin receptors
- lhtropin receptors
- ljtropin receptors
- litropin receptors
- l8tropin receptors
- l7tropin receptors
- lurropin receptors
- lufropin receptors
- lugropin receptors
- luyropin receptors
- lu6ropin receptors
- lu5ropin receptors
- luteopin receptors
- lutdopin receptors
- lutfopin receptors
- luttopin receptors
- lut5opin receptors
Etymology of LUTROPIN RECEPTORS
The term "Lutropin Receptors" is derived from two components - "lutropin" and "receptors".
1. Lutropin: The word "lutropin" refers to a hormone known as luteinizing hormone (LH) or human chorionic gonadotropin (hCG). The term "lutropin" originated from two Latin words - "lutum" meaning "mud" and "ropus" meaning "humor" or "fluid". Since LH is involved in the regulation of the menstrual cycle and the development and maintenance of the corpus luteum in females, the term "lutropin" is used to describe this hormone.
2. Receptors: The term "receptors" is derived from the Latin word "receptus", which means "received".
