The spelling of the word "loxoclase" is unique and can be explained using phonetic transcription. The first syllable "lox" is pronounced /lɑks/ with a long "o" sound, followed by the "ks" sound. The second syllable, "o" is pronounced /əʊ/ with a long vowel sound. The final syllable "clase" is pronounced /kleɪs/ with a long "a" sound and a silent "e" at the end. Therefore, the correct phonetic pronunciation of "loxoclase" is /lɑksəʊkleɪs/.
A variety of orthoclase, containing a large proportion of soda.
Etymological and pronouncing dictionary of the English language. By Stormonth, James, Phelp, P. H. Published 1874.