LOBAR HOLOPROSENCEPHALY Meaning and
Definition
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Lobar holoprosencephaly is a rare developmental disorder that affects the brain and central nervous system. It is characterized by the incomplete separation of the cerebral hemispheres during early embryonic development.
The term "lobar" refers to the lobes of the brain, which are distinct regions responsible for specific functions such as cognition, motor control, and sensory perception. In lobar holoprosencephaly, these lobes fail to fully divide, resulting in a single, fused structure or partially separated lobes in the front portion of the brain, known as the cerebral cortex.
Holoprosencephaly is a broader term that encompasses a spectrum of brain malformations resulting from the incomplete division of the forebrain. Lobar holoprosencephaly is one of the subtypes and is considered less severe than other forms such as semilobar or alobar holoprosencephaly.
This condition is typically present at birth and can vary in severity. Individuals affected by lobar holoprosencephaly often exhibit a range of physical and intellectual disabilities, including facial abnormalities, developmental delays, seizures, hearing loss, and vision problems. The specific symptoms and severity can differ widely among individuals, even within the same family.
Lobar holoprosencephaly is thought to result from a combination of genetic and environmental factors, although the exact cause is still unknown. It can occur sporadically or be inherited in an autosomal dominant or autosomal recessive manner, depending on the genetic mutations involved.
Currently, there is no cure for lobar holoprosencephaly. Treatment focuses on managing the individual's symptoms and providing supportive care to improve their quality of life. Multidisciplinary medical interventions and therapies involving neurologists,
Common Misspellings for LOBAR HOLOPROSENCEPHALY
- kobar holoprosencephaly
- pobar holoprosencephaly
- oobar holoprosencephaly
- libar holoprosencephaly
- lkbar holoprosencephaly
- llbar holoprosencephaly
- lpbar holoprosencephaly
- l0bar holoprosencephaly
- l9bar holoprosencephaly
- lovar holoprosencephaly
- lonar holoprosencephaly
- lohar holoprosencephaly
- logar holoprosencephaly
- lobzr holoprosencephaly
- lobsr holoprosencephaly
- lobwr holoprosencephaly
- lobqr holoprosencephaly
- lobae holoprosencephaly
- lobad holoprosencephaly
- lobaf holoprosencephaly
Etymology of LOBAR HOLOPROSENCEPHALY
The word "lobar holoprosencephaly" is derived from two components: "lobar" and "holoprosencephaly".
1. Lobar: The term "lobar" comes from the Latin word "lobus", meaning "lobe". In medical terminology, "lobar" refers to a lobe or a segment of an organ. In the context of "lobar holoprosencephaly", "lobar" refers to the brain's lobes specifically.
2. Holoprosencephaly: This term is composed of two Greek roots. "Holo" means "entire" or "whole", while "prosencephaly" refers to the forebrain.
