LIPOLIPOIDOSIS Meaning and
Definition
-
Lipolipoidosis is a rare inherited disorder characterized by the abnormal accumulation of certain lipids and lipoid substances within various tissues of the body. It is a type of lipid storage disease, also known as a sphingolipidosis, which belongs to a larger family of metabolic disorders called lysosomal storage diseases.
In lipolipoidosis, there is a deficiency or malfunction of specific lysosomal enzymes responsible for breaking down lipids and lipoid substances. As a result, these substances build up excessively within the cells of tissues such as the liver, spleen, lungs, and central nervous system.
The over-accumulation of lipids and lipoid substances leads to progressive damage and dysfunction of affected organs and tissues. This can manifest as a range of symptoms, including hepatosplenomegaly (enlargement of the liver and spleen), respiratory difficulties, neurological impairments, and developmental delays. The severity and specific clinical features of lipolipoidosis vary depending on the specific subtype.
Diagnosis of lipolipoidosis typically involves a combination of clinical evaluations, imaging techniques, and laboratory tests to identify the specific lipid markers and enzyme deficiencies associated with the condition. Treatment options for lipolipoidosis are limited and primarily focus on managing symptoms and slowing disease progression. Supportive measures may include medications, physical therapy, and interventions to address specific organ dysfunction.
Overall, lipolipoidosis is a complex and heterogeneous disorder that requires specialized medical attention and multidisciplinary care.
-
Fatty infiltration, both neutral fats and anisotropic lipoids being present in the cells.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
Common Misspellings for LIPOLIPOIDOSIS
- lipolipoidosas
- lipolipoidosms
- lipolipoidoshs
- lipolipoidosi3
- lipolipoidosic
- lipolipoidosiq
- lipolipoidosir
- lipolipoidewsis
- lipolipoiduesis
- l ipolipoidosis
- lipo lipoidosis
- lipol ipoidosis
- lipolipo idosis
- lipolipoi dosis
- lipolipoid osis
- lipolipoido sis
- lipolipoidos is
- lipolipoidosi s
Etymology of LIPOLIPOIDOSIS
The word "lipolipoidosis" is derived from three roots:
1. "Lipo-" comes from the Greek word "lipos" meaning "fat" or "lipid".
2. "Lipoid-" comes from the Greek word "lipos" meaning "fat" or "lipid" as well. The addition of "-oid" indicates a resemblance or similarity to something.
3. "-osis" is a suffix used in medical terminology to indicate a state, condition, or abnormal process.
So, when combined, "lipolipoidosis" refers to a condition or abnormal process that involves a similarity or resemblance to lipids or fats.
