LEUKOSTASIS SYNDROMES Meaning and
Definition
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Leukostasis syndromes are a group of medical conditions characterized by the abnormal accumulation of white blood cells (leukocytes) within the blood vessels. Specifically, these syndromes involve the excessive clustering or adherence of leukocytes to the lining of blood vessels, leading to impaired blood flow and potentially serious complications.
Leukostasis syndromes are most commonly associated with high numbers of immature white blood cells, particularly in the context of acute leukemia or acute myelogenous leukemia. However, they can also occur in other conditions involving a high white blood cell count, such as chronic myelogenous leukemia, myelodysplastic syndromes, or elevated leukocyte production due to inflammatory processes.
When leukocytes adhere to the vascular endothelium, they obstruct the normal circulation of blood, leading to decreased tissue perfusion and potentially life-threatening consequences. Common clinical manifestations of leukostasis syndromes include respiratory distress, neurological abnormalities, organ dysfunction, and increased susceptibility to bleeding or infections.
The prompt recognition and urgent treatment of leukostasis syndromes are crucial to prevent complications and improve patient outcomes. Treatment typically involves immediate initiation of leukapheresis, a procedure that removes excess white blood cells from the bloodstream. Concurrently, efforts are made to address the underlying cause of elevated white blood cell count, such as intensive chemotherapy or other targeted therapies. Supportive measures such as oxygen supplementation, fluid management, and prophylactic antibiotics may also be necessary in managing the complications associated with leukostasis syndromes.
Common Misspellings for LEUKOSTASIS SYNDROMES
- keukostasis syndromes
- peukostasis syndromes
- oeukostasis syndromes
- lwukostasis syndromes
- lsukostasis syndromes
- ldukostasis syndromes
- lrukostasis syndromes
- l4ukostasis syndromes
- l3ukostasis syndromes
- leykostasis syndromes
- lehkostasis syndromes
- lejkostasis syndromes
- leikostasis syndromes
- le8kostasis syndromes
- le7kostasis syndromes
- leujostasis syndromes
- leumostasis syndromes
- leulostasis syndromes
- leuoostasis syndromes
- leuiostasis syndromes
Etymology of LEUKOSTASIS SYNDROMES
The word "leukostasis syndromes" is derived from two primary components: "leuko-" and "-stasis".
1. Leuko-: The prefix "leuko-" is derived from the Greek word "leukos", meaning "white". It is commonly used in scientific terminology in reference to white blood cells or related to diseases involving them.
2. -Stasis: The suffix "-stasis" originates from the Greek word "stasis", which means "standing" or "stoppage". It is often used in medical terminology to describe a state of halted or interrupted flow of blood or other bodily fluids.
When these components are combined, the term "leukostasis" refers to a medical condition where there is the abnormally high level of white blood cells in the circulation, leading to vessel obstruction or impaired blood flow.
