LEUCYL AMINOPEPTIDASE Meaning and
Definition
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Leucyl aminopeptidase is an enzyme that belongs to the family of metallopeptidases, specifically the aminopeptidase M-like family. It is primarily found in different tissues throughout the body, including the kidneys, intestines, and liver, where it plays a crucial role in the metabolism of peptides.
This enzyme is responsible for the hydrolysis of leucine residues from the N-terminus of peptides and proteins. It acts by cleaving the peptide bond between the leucine amino acid and the neighboring residue, releasing free leucine. Leucyl aminopeptidase is highly specific for leucine residues and does not hydrolyze other amino acids.
The activity of this enzyme is regulated by various factors, including pH, temperature, and the presence of co-factors. It exhibits its optimal activity in a slightly acidic to neutral pH range. Additionally, it requires divalent metal ions, such as zinc or cobalt, as co-factors for catalytic activity.
Leucyl aminopeptidase has been implicated in several physiological processes, including the regulation of blood pressure, digestion, and immune response. It is also involved in the catabolism of bioactive peptides and neuropeptides, such as bradykinin and substance P. Dysfunction or altered levels of leucyl aminopeptidase have been associated with certain diseases, such as hypertension, inflammatory bowel disease, and cancer.
In summary, leucyl aminopeptidase is an enzyme that cleaves leucine residues from the N-terminus of peptides and proteins, playing important roles in peptide metabolism and various physiological processes.
Common Misspellings for LEUCYL AMINOPEPTIDASE
- keucyl aminopeptidase
- peucyl aminopeptidase
- oeucyl aminopeptidase
- lwucyl aminopeptidase
- lsucyl aminopeptidase
- lducyl aminopeptidase
- lrucyl aminopeptidase
- l4ucyl aminopeptidase
- l3ucyl aminopeptidase
- leycyl aminopeptidase
- lehcyl aminopeptidase
- lejcyl aminopeptidase
- leicyl aminopeptidase
- le8cyl aminopeptidase
- le7cyl aminopeptidase
- leuxyl aminopeptidase
- leuvyl aminopeptidase
- leufyl aminopeptidase
- leudyl aminopeptidase
- leuctl aminopeptidase
Etymology of LEUCYL AMINOPEPTIDASE
The word "Leucyl Aminopeptidase" has its etymology derived from Greek and Latin roots.
The term "leucyl" stems from the Greek word "leukos", which means "white". In this context, it refers to the amino acid leucine.
The word "aminopeptidase" is a combination of two parts. "Amino" is derived from the Latin "amino", meaning "amine" or "nitrogen-containing compound". "Peptidase" comes from the Latin "peptidum", which refers to a small protein. Together, "aminopeptidase" describes an enzyme that catalyzes the removal of an amino acid from the amino (NH2) terminus of a peptide or protein.
