Leprosy, also known as Hansen's disease, is a chronic infectious disease caused by the Mycobacterium leprae bacterium. The spelling of "leprosy bacillus" can be explained using the International Phonetic Alphabet (IPA). "Leprosy" is pronounced /ˈlep.rə.si/, with stress on the first syllable. "Bacillus" is pronounced /bəˈsɪləs/, with stress on the second syllable. When both words are combined, the stress remains on the first syllable of "leprosy", resulting in the transcription /ˈlep.rə.si bəˈsɪləs/.
Leprosy bacillus, scientifically known as Mycobacterium leprae, is a bacterium that causes leprosy, a chronic infectious disease that primarily affects the skin and peripheral nerves. This slow-growing, acid-fast bacterium belongs to the genus Mycobacterium and is specifically adapted to infect and multiply within human hosts.
Leprosy bacillus is transmitted through prolonged close contact with an infected individual, mainly through respiratory droplets. However, the exact mode of transmission is still not well understood. It primarily multiplies within an infected person's cool body regions, such as the skin, nasal mucosa, and peripheral nerves.
The bacterium is highly persistent, with a slow reproduction rate, which is one of the reasons why leprosy has a long incubation period. Once the infection occurs, symptoms may take years or even decades to emerge. Common signs of leprosy include skin lesions, impaired sensation, nerve damage, and in severe cases, deformities and disfigurements.
Leprosy bacillus is unique in its ability to evade the immune system, allowing it to persist within the human body. This is partly due to its waxy cell wall, which provides protection against various substances, including antibiotics. As a result, leprosy requires a multidrug treatment regimen typically lasting several months to years to completely eradicate the bacterium from the body.
Efforts have been made to develop new diagnostic tools and more effective treatments for leprosy bacillus, aiming to control and eliminate this ancient disease that still affects marginalized populations in various parts of the world.
The etymology of the word "leprosy" can be traced back to Greek and Latin roots. The term "leprosy" is derived from the Ancient Greek word "lepra" (λέπρα), meaning "scaly skin" or "scales". This Greek word, in turn, comes from the Proto-Indo-European root "*lep-", which meant "to peel" or "to tear off". In Latin, the term "lepra" was transformed into "lepra" in classical Latin and eventually into "leprosie" in medieval Latin, which later evolved into "leprosy" in English.
The term "bacillus" on the other hand, originates from Latin. It comes from the Latin word "bacillum", which means "little staff" or "little rod".