LEPORE HAEMOGLOBIN Meaning and
Definition
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Lepore hemoglobin is a specific type of abnormal hemoglobin molecule found in individuals with a rare genetic blood disorder known as thalassemia. Hemoglobin is a protein molecule responsible for carrying oxygen throughout the body via red blood cells. In thalassemia, there is a deficiency or malfunction in the genes that control the production of hemoglobin, leading to the synthesis of abnormal versions of the molecule.
Lepore hemoglobin is characterized by its formation through a genetic mutation that involves the fusion of elements from both the alpha and beta chains of hemoglobin. This fusion results in an abnormal structure and function of the hemoglobin molecule, affecting its ability to efficiently carry and deliver oxygen to tissues.
Individuals who inherit this genetic mutation from both parents may develop a specific form of thalassemia called Lepore hemoglobinopathy, which presents with variable symptoms ranging from mild to severe anemia. The severity of the condition depends on the specific genetic mutation and the amount of functional hemoglobin produced.
Diagnosis of Lepore hemoglobin is typically confirmed through laboratory tests that analyze the structure and function of hemoglobin molecules in the blood. Treatment options for Lepore hemoglobinopathy may include regular blood transfusions, iron chelation therapy to manage excess iron levels from transfusions, and in some cases, bone marrow transplantation. Close monitoring and management by a hematologist or specialized medical professional are essential to ensure the well-being and quality of life of individuals affected by Lepore hemoglobinopathy.
Common Misspellings for LEPORE HAEMOGLOBIN
- kepore haemoglobin
- pepore haemoglobin
- oepore haemoglobin
- lwpore haemoglobin
- lspore haemoglobin
- ldpore haemoglobin
- lrpore haemoglobin
- l4pore haemoglobin
- l3pore haemoglobin
- leoore haemoglobin
- lelore haemoglobin
- le0ore haemoglobin
- lepire haemoglobin
- lepkre haemoglobin
- leplre haemoglobin
- leppre haemoglobin
- lep0re haemoglobin
- lep9re haemoglobin
- lepoee haemoglobin
- lepode haemoglobin
Etymology of LEPORE HAEMOGLOBIN
"Lepore haemoglobin" is a specific type of haemoglobin variant named after the family whose members were first found to exhibit this variant. It is derived from the surname "Lepore" and the term "haemoglobin".
The Lepore family, of Italian descent, came into prominence in the study of haemoglobin variants when members of the family were found to have a unique form of haemoglobin. This variant was initially discovered in 1958 in a study conducted by Dr. Frank Lepor (also spelled Lepore) and his colleagues. The Lepore family members had a unique condition in which their haemoglobin structure differed from that of normal individuals.
Haemoglobin, on the other hand, is the protein responsible for carrying oxygen in red blood cells. It is derived from the Greek words "haima" meaning "blood" and "globin" meaning "protein".
