LAYER OF LANGHANS Meaning and
Definition
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Layer of Langhans refers to a characteristic histological feature observed in certain types of tissues and cells. Specifically, it is a term commonly used to describe a specific cellular layer that appears as a distinct arrangement of cells within tissues or cellular structures. The term is most frequently associated with the layer of cells seen in granulomas and tuberculous lesions.
The layer of Langhans is named after German scientist Theodor Langhans, who first described this cellular arrangement in 1868. It is typically composed of epithelioid cells, which are derived from macrophages that have transformed into a distinctive appearance resembling epithelial cells. These epithelioid cells are elongated and arranged in a palisade-like formation, where they align in parallel rows or columns.
The presence of the layer of Langhans in tissue sections is often a key diagnostic indicator for certain pathological conditions, such as tuberculosis and sarcoidosis. It is particularly associated with granulomatous inflammation, which is characterized by the aggregation of macrophages and the formation of granulomas – immune cell clusters that attempt to wall off foreign substances or infectious agents within tissues.
In summary, the layer of Langhans is a distinct cellular arrangement characterized by elongated epithelioid cells forming parallel rows or columns. Its presence in tissues is often indicative of granulomatous inflammation, and it is frequently observed in conditions such as tuberculosis and sarcoidosis.
Common Misspellings for LAYER OF LANGHANS
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- layee of langhans
