Lactic Dehydrogenase Viruses (LDH viruses) are a group of viruses that primarily target and infect cells of the mammalian lactic dehydrogenase enzyme, also known as lactate dehydrogenase (LDH). LDH is an essential enzyme involved in the conversion of lactate to pyruvate in the process of cellular energy production.
LDH viruses have been identified to include various strains of viral pathogens, such as retroviruses and RNA viruses, that specifically target LDH isoforms found in various tissues and organs of mammals, including humans. These viruses can cause infections characterized by the disruption of LDH activity and subsequent impairments in cellular metabolism.
While LDH viruses can vary in their pathogenicity, some strains have been found to be associated with significant health issues in affected individuals. These viruses can cause a range of symptoms, depending on the affected tissues or organs, including fever, fatigue, muscle pain, organ dysfunction, and in severe cases, life-threatening complications.
Diagnosis of LDH viral infections typically involves assessing the activity levels of LDH in the affected tissues, alongside the identification of the specific viral strain through molecular techniques like polymerase chain reaction (PCR). Currently, treatment options for LDH viral infections are limited, and management primarily focuses on relieving symptoms and providing supportive care.
Further research is ongoing to better understand the mechanisms of LDH virus-host interactions, viral replication, and potential therapeutic interventions.
