KUPFFER CELL Meaning and
Definition
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Kupffer cells are highly specialized immune cells found in the liver. They are classified as macrophages, which are responsible for engulfing and digesting foreign substances, cellular debris, and pathogens within the body. Kupffer cells, specifically, play a crucial role in the liver's immune defense system.
These cells reside within the hepatic sinusoids, which are the tiny blood vessels that carry blood through the liver. Kupffer cells are strategically positioned along the sinusoids to monitor the blood flowing through, allowing them to patrol and intercept any potential pathogens or toxins that may enter the liver.
Their primary function is phagocytosis, the process of engulfing and destroying foreign substances. When Kupffer cells detect bacteria, viruses, or other harmful agents, they extend their branches or pseudopodia to capture and engulf them. Once engulfed, Kupffer cells break down and eliminate these pathogens through enzymatic digestion.
Additionally, Kupffer cells contribute to immune regulation within the liver by producing cytokines, which are small signaling molecules that coordinate immune responses. These cytokines help activate other immune cells, recruit additional immune cells to the liver when needed, and promote the inflammatory response necessary for defense against infections.
Overall, Kupffer cells are essential components of the liver's immune system, protecting this vital organ from potential harm and infection.
Common Misspellings for KUPFFER CELL
- jupffer cell
- mupffer cell
- lupffer cell
- oupffer cell
- iupffer cell
- kypffer cell
- khpffer cell
- kjpffer cell
- kipffer cell
- k8pffer cell
- k7pffer cell
- kuoffer cell
- kulffer cell
- ku0ffer cell
- kupdfer cell
- kupcfer cell
- kupvfer cell
- kupgfer cell
- kupfder cell
- kupfcer cell
Etymology of KUPFFER CELL
The word "Kupffer cell" is derived from the name of a German anatomist named Karl Wilhelm von Kupffer. He discovered these specific cells in the liver in the nineteenth century and described their morphology and functions. These cells were subsequently named after him to honor his contributions to the field of anatomy.
