KRUKENBERG TUMOR Meaning and
Definition
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Krukenberg tumor is a medical condition characterized by the presence of metastatic cancerous cells in the ovaries. It specifically refers to the spread of a primary tumor, typically originating from the gastrointestinal tract, to the ovaries. Named after Friedrich Ernst Krukenberg, the German physician who first described it in the early 20th century, Krukenberg tumor is often associated with advanced stages of cancer.
These tumors are formed when malignant cells detach from their original site and travel through the bloodstream or lymphatic system to reach the ovaries. Upon settling in the ovaries, these metastatic cells grow and form secondary tumors. Histologically, Krukenberg tumors are composed of signet ring cells, which are characterized by a large mucin-filled vacuole that displaces the nucleus towards the periphery.
Symptoms of Krukenberg tumor may include abdominal pain, bloating, weight loss, and irregular menstruation. Diagnosis often involves imaging studies, such as ultrasound, computed tomography (CT), or magnetic resonance imaging (MRI), as well as biopsy to confirm the presence of signet ring cells. Treatment depends on the extent of metastasis and can involve surgeries such as oophorectomy or debulking procedures, chemotherapy, and targeted therapies.
Prognosis for Krukenberg tumor is generally poor due to its presentation in advanced stages and the aggressive nature of the underlying primary cancers. However, early detection and prompt management can significantly improve the patient's quality of life and longevity.
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Fibrosarcoma mucocellulare (carcinomatodes) ovarii; a fibrosarcoma of the ovary which has undergone myxomatous degeneration involving both ground substance and cells, the former showing large loose meshes, the latter becoming swollen, pale, and faintly granular, with a deeply staining crescentic peripheral nucleus-presenting the so-called "seal-ring" form.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
Common Misspellings for KRUKENBERG TUMOR
- jrukenberg tumor
- mrukenberg tumor
- lrukenberg tumor
- orukenberg tumor
- irukenberg tumor
- keukenberg tumor
- kdukenberg tumor
- kfukenberg tumor
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- k5ukenberg tumor
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- krykenberg tumor
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- krujenberg tumor
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Etymology of KRUKENBERG TUMOR
The word "Krukenberg tumor" is named after Friedrich Ernst Krukenberg, a German physician who first described this type of tumor in 1896. Friedrich Krukenberg was a renowned pathologist and surgeon who worked at the University of Bonn and later became the director of the Surgical Pathology Department at the University of Strasbourg. He conducted extensive research on tumors and made significant contributions to the field of pathology. As a result, the term "Krukenberg tumor" is used to refer to a specific type of malignancy characterized by metastasis of gastrointestinal cancer, primarily originating from the stomach, to the ovaries.
