How Do You Spell KIRSTEN MURINE SARCOMA VIRUS?

Pronunciation: [kˈɜːstən mjˈʊɹiːn sɑːkˈə͡ʊmə vˈa͡ɪɹəs] (IPA)

The spelling of "Kirsten murine sarcoma virus" can be a bit tricky, but using the International Phonetic Alphabet (IPA) can help make it clear. The first syllable of Kirsten is pronounced /ˈkɪərstən/, with a long "i" sound and a stressed "e". Murine is pronounced /ˈmjʊəriːn/, with the emphasis on the first syllable and a long "u" sound. Sarcoma is pronounced /sɑːrˈkəʊmə/, with the emphasis on the second syllable and a short "o" sound. Finally, virus is pronounced /ˈvaɪrəs/, with the emphasis on the first syllable and a long "i" sound.

KIRSTEN MURINE SARCOMA VIRUS Meaning and Definition

1. Kirsten murine sarcoma virus, also known as Kirsten virus or K-ras, is a type of retrovirus belonging to the oncogenic family of viruses. It was first discovered and isolated from a mouse with sarcoma in the 1960s by Dr. Werner Kirsten. This virus has become widely studied due to its association with the development of cancer.

   Kirsten murine sarcoma virus possesses an RNA genome that gets reverse transcribed into DNA upon infection of the host cells. It primarily infects and transforms mammalian cells, causing the uncontrolled growth and proliferation commonly associated with cancer. The viral genome integrates into the host cell's DNA, altering its normal functions.

   Once integrated, the virus activates the expression of certain oncogenes, specifically the Kirsten rat sarcoma (K-ras) genes, which play a crucial role in cell signaling and growth regulation. These genes become permanently switched on, leading to the development and progression of cancerous tumors.

   The association of Kirsten murine sarcoma virus with cancer has extensively been studied in animal models, particularly in mice. The insights gained from these studies have contributed significantly to our understanding of the molecular mechanisms underlying cancer development and progression.

   Kirsten murine sarcoma virus serves as a valuable tool in cancer research and has facilitated the development of experimental models, therapeutics, and diagnostic techniques.

Common Misspellings for KIRSTEN MURINE SARCOMA VIRUS

• jirsten murine sarcoma virus
• mirsten murine sarcoma virus
• lirsten murine sarcoma virus
• oirsten murine sarcoma virus
• iirsten murine sarcoma virus
• kursten murine sarcoma virus
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• korsten murine sarcoma virus
• k9rsten murine sarcoma virus
• k8rsten murine sarcoma virus
• kiesten murine sarcoma virus
• kidsten murine sarcoma virus
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• kitsten murine sarcoma virus
• ki5sten murine sarcoma virus
• ki4sten murine sarcoma virus
• kiraten murine sarcoma virus
• kirzten murine sarcoma virus
• kirxten murine sarcoma virus