KININOGENIN Meaning and
Definition
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Kininogenin is a noun that refers to a substance belonging to the class of kinins, which are peptide hormones that play a significant role in various physiological processes, especially in inflammation and blood pressure regulation.
In more specific terms, kininogenin is a precursor molecule that gives rise to kinins, such as bradykinin and kallidin. These kinins are activated through the proteolytic cleavage of kininogenin by enzymes called kallikreins. The release of kinins into the bloodstream or tissues leads to the stimulation of specific receptors, known as kinin receptors, contributing to the initiation and modulation of numerous biological responses.
Kininogenin is primarily produced in the liver and secreted into the blood circulation. It is considered an essential component of the kallikrein-kinin system, which functions as a mediator in different physiological and pathological conditions, encompassing inflammation, pain, blood vessel dilation, permeability changes, and smooth muscle contraction.
Additionally, kininogenin has been associated with various disease processes, including angioedema, hereditary angioedema, and certain cardiovascular disorders. Research on kininogenin and its derivatives continues to shed light on their potential therapeutic applications, such as being utilized as biomarkers for disease diagnosis and prognosis, as well as the development of novel drugs targeting the kallikrein-kinin system.
Overall, kininogenin plays a crucial role in the regulation of inflammatory responses and vascular homeostasis, highlighting its significance in physiology and disease.
Common Misspellings for KININOGENIN
- jininogenin
- mininogenin
- lininogenin
- oininogenin
- iininogenin
- kuninogenin
- kjninogenin
- kkninogenin
- koninogenin
- k9ninogenin
- k8ninogenin
- kibinogenin
- kiminogenin
- kijinogenin
- kihinogenin
- kinunogenin
- kinjnogenin
- kinknogenin
- kinonogenin
- kin9nogenin
Etymology of KININOGENIN
The word "Kininogenin" is a compound of two terms: "kininogen" and "in".
The term "kininogen" comes from the Greek word "kīnēsis", meaning "movement", and the combining form "-gen", which derives from the Greek "gignomai", meaning "to produce" or "to be born". Kininogens are a group of proteins found in the blood that are involved in various physiological functions, including the production of kinins, which are important mediators of inflammation and blood pressure regulation.
The suffix "in" is often used in chemistry to denote a specific compound or derivative.
