Kilham rat virus (KRV) is a type of virus that primarily affects laboratory and pet rats. It is a member of the Hantavirus genus, which belongs to the Bunyaviridae family. KRV was first discovered in the 1950s by Dr. Kenneth Kilham, a virologist, hence its name.
KRV has been extensively studied in laboratory settings due to its immunological and neurological effects on rats. It mainly infects the respiratory tract and spreads through respiratory secretions, feces, and urine. When transmitted to other rats, it can cause various symptoms, including fever, weight loss, lethargy, and respiratory distress.
While KRV is not known to cause significant illness in humans, it is zoonotic, meaning it can occasionally be transmitted from infected rats to humans. In humans, KRV infection can result in mild flu-like symptoms, such as fever, headache, and muscle ache. Severe cases with pulmonary involvement have also been reported, especially in individuals with weakened immune systems.
To prevent the transmission of KRV, it is crucial to take proper precautions when handling rats, especially in laboratory or pet settings. This includes practicing good hygiene, such as frequent handwashing, wearing gloves, and avoiding direct contact with rat bodily fluids. Additionally, maintaining a clean environment and regularly disinfecting rat cages and surfaces can help reduce the spread of the virus.
Overall, Kilham rat virus is a type of hantavirus that primarily affects rats, with potential zoonotic transmission to humans. It is important to handle rats with care and take appropriate measures to prevent its spread.
