Pronunciation: [kˈɛtəksˌa͡ɪm] (IPA) 
Ketoxime is spelled with the IPA phonetic transcription of /kiːtɒksɪm/. The first two letters "ke" represent the sound /kiː/ and are followed by "t" and "o" which make the sound /tɒ/. The letter "x" can be pronounced as either /ks/ or /gz/, in this case it is pronounced as /ks/. The letters "i" and "m" represent the sounds /ɪ/ and /m/ respectively. The final "e" is silent, making the stress fall on the second syllable.
Ketoxime is a chemical compound belonging to the oxime class of organic compounds. It is formed by the reaction of an aldehyde or a ketone with hydroxylamine, where a hydrogen atom on the carbon adjacent to the carbonyl group is replaced by hydroxylamine (-NOH) to form a specific type of oxime compound.
Ketoximes contain a C=N-OH functional group, in which the nitrogen atom is bonded to a carbon atom on one side and to an oxygen atom on the other side. This unique chemical structure imparts distinct properties to ketoximes and contributes to their various applications in organic synthesis.
Ketoximes are commonly used in organic chemistry as versatile reagents. They serve as intermediates in the synthesis of various pharmaceuticals, agrochemicals, and fine chemicals. Furthermore, ketoximes can undergo a rearrangement reaction to form the corresponding amides, providing a useful method for the synthesis of amides.
In addition, ketoximes have unique physiological properties that make them significant in pharmacology. They possess potential antioxidant properties and have been studied for their ability to scavenge free radicals and protect against oxidative stress-related diseases.
Overall, ketoximes are valuable compounds in various fields, including organic synthesis, pharmaceuticals, and pharmacological research, due to their distinctive chemical structure and versatile applications.
The word "ketoxime" is derived from a combination of two terms: "ketone" and "oxime".
- "Ketone" refers to a type of organic compound that contains a carbonyl functional group (C=O) bonded to two alkyl or aryl groups. The term "ketone" itself comes from the German word "Keton", which was coined by Hermann Kolbe in 1851.
- "Oxime" refers to a functional group (-C=N-OH) that is attached to a carbon atom. The term "oxime" originated from the combination of the Latin word "oximus" (meaning sharpest, acutest) and the Greek word "oxyma" (meaning acid drink).
