KEOXIFENE Meaning and
Definition
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Keoxifene is a synthetic compound belonging to the class of selective estrogen receptor modulators (SERMs). It is primarily used in the treatment and prevention of osteoporosis, a condition characterized by weakened and brittle bones. Keoxifene acts by binding to estrogen receptors in certain tissues, such as bone, and helps to reduce bone loss and increase bone density.
The mechanism of action of Keoxifene involves both estrogenic and antiestrogenic effects. In tissues with a high concentration of estrogen receptors, such as the bone, Keoxifene acts as an estrogen agonist, mimicking the effects of estrogen. This results in increased bone mineral density and reduced bone turnover. However, in other tissues such as the breast, Keoxifene acts as an estrogen antagonist, blocking the effects of estrogen and reducing the risk of estrogen-related diseases such as breast cancer.
Keoxifene is primarily metabolized in the liver and excreted mainly through feces. It has a long half-life, allowing for once-daily administration. Common side effects of Keoxifene may include hot flashes, leg cramps, and an increased risk of blood clots.
Overall, Keoxifene is an important pharmaceutical agent used in the management of osteoporosis. By selectively modulating estrogen receptors in specific tissues, Keoxifene provides beneficial effects on bone health while minimizing the potential risks associated with unopposed estrogen exposure.
Common Misspellings for KEOXIFENE
- jeoxifene
- meoxifene
- leoxifene
- oeoxifene
- ieoxifene
- kwoxifene
- ksoxifene
- kdoxifene
- kroxifene
- k4oxifene
- k3oxifene
- keixifene
- kekxifene
- kelxifene
- kepxifene
- ke0xifene
- ke9xifene
- keozifene
- keocifene
- keodifene
