KARTAGENER TRIADS Meaning and
Definition
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Kartagener triads, also known as Kartagener syndrome or primary ciliary dyskinesia, is a rare genetic disorder characterized by a set of three main clinical features: chronic sinusitis, bronchiectasis, and situs inversus. This condition is inherited in an autosomal recessive pattern, meaning that an individual must inherit two abnormal copies of the gene associated with the disorder, one from each parent, in order to be affected.
One of the key components of Kartagener triads is chronic sinusitis, referring to inflammation or infection of the sinuses that results in long-term nasal congestion, facial pressure, and recurring nasal discharge. Bronchiectasis, another hallmark of this condition, involves the irreversible dilation and damage to the bronchial tubes in the lungs. This leads to persistent coughing, sputum production, and recurrent respiratory infections.
Additionally, Kartagener triads are typically associated with situs inversus, a condition in which the internal organs are arranged in a mirror-image reversal of their usual positions within the body. For example, the heart may be located on the right side instead of the left, and the liver on the left rather than the right.
People with Kartagener triads may also experience fertility issues, as the motility of sperm and fallopian tubes can be affected due to the abnormal ciliary function. Other potential symptoms may include hearing loss, dizziness, and recurrent ear infections.
Although there is no cure for Kartagener triads, management focuses on controlling the symptoms and preventing complications through various interventions, such as airway clearance techniques, antibiotics to treat infections, and surgical procedures, if necessary. Genetic counseling is also recommended for affected individuals and their families to understand the inheritance pattern and discuss the risk of
Common Misspellings for KARTAGENER TRIADS
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Etymology of KARTAGENER TRIADS
The term Kartagener triads is named after a renowned Swiss physician named Manes Kartagener (1897-1975). He first described a set of clinical features that now bear his name in 1933.
The word Kartagener is derived from the individual Kartagener's last name. The etymology of the surname itself is German or Swiss German. It is difficult to establish its exact meaning without knowing the specific origins or dialect of the name. In general, surnames often derive from ancestral occupations, locations, or personal characteristics, but without more information, it is challenging to determine the precise etymology for the name Kartagener.
