KALLIKREINOGEN Meaning and
Definition
-
Kallikreinogen is a substance that is a precursor or inactive form of the enzyme kallikrein. Kallikreinogen is primarily produced and secreted by various tissues and organs, such as the pancreas, kidneys, and salivary glands. It plays an important role in the regulation of a variety of physiological processes throughout the body.
When kallikreinogen is activated by specific enzymes or factors, it undergoes a biochemical reaction to transform into its active form, known as kallikrein. Kallikrein, in turn, functions as a serine protease enzyme that catalyzes the hydrolysis of proteins or peptides at specific sites.
The conversion of kallikreinogen into kallikrein is often triggered by various factors, such as tissue injury, inflammation, hormonal stimulation, or other biochemical signals present in the body. Once activated, kallikrein plays a significant role in numerous biological processes, including blood pressure regulation, blood coagulation, inflammation, immune response modulation, and pain perception.
The measurement of kallikreinogen levels in biological samples, such as blood or urine, can be useful in the diagnosis and monitoring of certain diseases or conditions. Abnormal levels of kallikreinogen may indicate specific pathological conditions, such as pancreatic disorders, renal diseases, or urinary tract infections.
In summary, kallikreinogen is an inactive precursor molecule that gets transformed into its active form, kallikrein, which acts as a key enzyme involved in various physiological processes.
Common Misspellings for KALLIKREINOGEN
- jallikreinogen
- mallikreinogen
- lallikreinogen
- oallikreinogen
- iallikreinogen
- kzllikreinogen
- ksllikreinogen
- kwllikreinogen
- kqllikreinogen
- kaklikreinogen
- kaplikreinogen
- kaolikreinogen
- kalkikreinogen
- kalpikreinogen
- kaloikreinogen
- kallukreinogen
- kalljkreinogen
- kallkkreinogen
- kallokreinogen
- kall9kreinogen
Etymology of KALLIKREINOGEN
The word "Kallikreinogen" is derived from the combination of two terms: "kallikrein" and "ogen".
The term "kallikrein" comes from the Greek words "kalli-" meaning "beautiful" or "noble" and "krein" meaning "to separate or secrete". It was coined by the German biochemist and Nobel laureate, Otto René Maier, in 1938. Kallikreins are a group of proteolytic enzymes found in the human body that are involved in various physiological processes, such as blood pressure regulation, inflammation, and tissue repair.
The suffix "-ogen" is commonly used in biology to indicate a precursor or an inactive form of a substance.
