JONES REAGENT Meaning and
Definition
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Jones reagent refers to a powerful and commonly used oxidizing reagent in organic chemistry. It derives its name from its discoverer, Sir Ewart Jones, a renowned British chemist. The Jones reagent is primarily composed of a mixture of chromic trioxide (CrO3) and concentrated sulfuric acid (H2SO4). This reagent works as an oxidizing agent by enabling the transfer of oxygen atoms to the substrate molecules, resulting in the oxidation of various functional groups.
The Jones reagent finds extensive application in various organic transformations. It is particularly useful for oxidizing primary and secondary alcohols to aldehydes and ketones, respectively. The reaction mechanism involves the initial formation of a chromate ester by the addition of the alcohol to the reagent. This intermediate then undergoes hydrolysis, resulting in the desired oxidation product. Additionally, the Jones reagent can also oxidize other functional groups, such as thiols to disulfides and aldehydes to carboxylic acids.
Due to its strong oxidizing properties, the Jones reagent must be handled with caution. It is highly corrosive and can cause severe burns and damage to organic materials. Additionally, its disposal must adhere to strict safety protocols, as it is considered hazardous waste.
In summary, the Jones reagent is a potent oxidizing reagent used in organic chemistry for the conversion of alcohols to aldehydes or ketones. Its effectiveness and versatility have made it a valuable tool in various synthetic transformations, while its potential hazards necessitate careful handling and disposal procedures.
Etymology of JONES REAGENT
The term "Jones reagent" is named after Sir Ewart Jones, a British chemist who developed and published the reagent in the 1950s. The reagent, also known as the "chromic acid mixture", consists of a solution of chromic acid in sulfuric acid. It is commonly used in organic chemistry for the oxidation of alcohols to carbonyl compounds, among other reactions.
