How Do You Spell JOB SYNDROME?

Pronunciation: [d͡ʒˈɒb sˈɪndɹə͡ʊm] (IPA)

The correct spelling of the medical condition known as "Job Syndrome" is often misspelled as "Job's Syndrome." The correct phonetic transcription is ʤɒb ˈsɪndrəʊm. The name is derived from the patient that it was first identified in, whose last name was "Job." However, the possessive form of the name, "Job's," is not needed in this case. The condition is actually named after the initials of the patient's first, middle, and last names (Job's Syndrome would be J.S.'s Syndrome).

JOB SYNDROME Meaning and Definition

1. Job Syndrome, also known as Hyper IgE syndrome (HIES), is a rare primary immunodeficiency disorder characterized by recurring infections, eczema, and elevated levels of immunoglobulin E (IgE) in the blood.

   Individuals with Job Syndrome usually present with a distinctive facial appearance, including wide-spaced eyes, a broad nose, and a prominent forehead. They are prone to bacterial and fungal infections of the skin, lungs, and other organs. These infections are often severe and recurrent, leading to chronic lung damage, abscesses, and other complications.

   Moreover, patients with Job Syndrome commonly develop eczema, a chronic inflammatory skin condition characterized by itchy, red, and scaly patches. This can further contribute to the risk of skin infections. Additionally, affected individuals are more susceptible to allergies, particularly to environmental or food allergens.

   Besides the characteristic clinical features, Job Syndrome can be further diagnosed through laboratory tests, such as the measurement of IgE levels, which are significantly elevated in affected individuals. Genetic testing may also be performed to confirm the presence of mutations in genes associated with the disorder.

   Treatment of Job Syndrome is focused on managing the specific symptoms and preventing complications. Antibiotic and antifungal medications are commonly prescribed to control infections, while regular monitoring of IgE levels can guide the treatment approach. Additionally, preventive measures like vaccinations and minimizing exposure to potential triggers, such as allergens, are essential for managing the condition.

   In conclusion, Job Syndrome is an uncommon immunodeficiency disorder characterized by recurrent infections, eczema, and elevated IgE levels. Early diagnosis and appropriate management are crucial for improving the quality of life and survival of individuals with this syndrome.

Common Misspellings for JOB SYNDROME

• hob syndrome
• nob syndrome
• mob syndrome
• kob syndrome
• iob syndrome
• uob syndrome
• jib syndrome
• jkb syndrome
• jlb syndrome
• jpb syndrome
• j0b syndrome
• j9b syndrome
• jov syndrome
• jon syndrome
• joh syndrome
• jog syndrome
• job ayndrome
• job zyndrome
• job xyndrome
• job dyndrome

Etymology of JOB SYNDROME

The term "Job syndrome" is derived from the name of a unique condition called "hyper IgE syndrome" or "Job's syndrome". It is named after an early patient named Job who was described in a 1966 medical article. The syndrome was first identified as a distinct immunodeficiency disorder in the 1960s by Dr. Robert Good and his colleagues. The exact reason behind the choice of the name "Job" is unclear and whether it refers to a biblical reference or an arbitrary name chosen for the patient is uncertain. Nevertheless, the term "Job syndrome" has been widely accepted to refer to this specific immunodeficiency disorder.