ISOSORBIDE MONONITRATE Meaning and
Definition
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Isosorbide mononitrate is a pharmaceutical compound used primarily in the treatment and prevention of angina pectoris, a condition caused by decreased blood flow to the heart due to narrowed arteries. It belongs to a class of drugs known as nitrates, which act as vasodilators to widen blood vessels and improve blood flow.
Isosorbide mononitrate works by converting into nitric oxide once in the body. Nitric oxide relaxes and dilates the smooth muscles within the blood vessels, reducing the workload on the heart and improving blood supply to the heart muscle. This mechanism of action helps to relieve episodes of chest pain associated with angina and reduces the frequency and severity of angina attacks over time.
The compound is typically administered orally as an extended-release tablet or capsule, allowing for a more gradual release of the medication into the bloodstream and providing long-lasting effects. The dosage is often tailored to the individual patient's needs, as determined by their healthcare provider.
Although isosorbide mononitrate is generally well-tolerated, there may be potential side effects such as headaches, dizziness, flushing, and low blood pressure. Patients with certain conditions, such as severe anemia, hypotension, or recent heart attack, may require special caution when using this medication.
Overall, isosorbide mononitrate is an effective therapeutic option for managing angina symptoms and improving overall heart health in appropriate patients. As with any medication, it is important to follow the prescribed dosage and consult with a healthcare professional for personalized advice.
Etymology of ISOSORBIDE MONONITRATE
The word "isosorbide mononitrate" has its etymology derived from two separate components: "isosorbide" and "mononitrate".
1. Isosorbide: The term "isosorbide" originates from the fusion of two Greek words: "iso", meaning equal, and "sorbide", which refers to sorbitol (a type of sugar alcohol). Sorbitol is used as a starting material in the synthesis of isosorbide. Therefore, "isosorbide" can be understood as a compound similar to sorbitol.
2. Mononitrate: "Mononitrate" is a term formed by combining "mono", meaning one, and "nitrate". Nitrate refers to an ion composed of one nitrogen atom bonded to three oxygen atoms.
