ISOQUINOLINES Meaning and
Definition
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Isoquinolines are a class of organic compounds that belong to the larger group of heterocyclic compounds, which are characterized by having atoms of at least two different elements in their ring structure. The isoquinoline structure consists of a benzene ring fused with a pyridine ring, resulting in a fused bicyclic structure. Isoquinolines are commonly found in various natural products, such as alkaloids, which are compounds known for their pharmacological activities.
Synthetically, isoquinolines can be prepared by several methods, including Pictet-Spengler condensation, Bischler-Napieralski reaction, or the Bischler-Möhlau reaction. Due to their structural diversity and biological activities, isoquinolines have drawn significant attention in medicinal chemistry and drug discovery. Many isoquinoline derivatives have exhibited various pharmacological properties, including anticancer, anti-inflammatory, antimicrobial, and antiviral activities.
Isoquinolines have also found utility as building blocks in the synthesis of complex organic molecules. The presence of the fused benzene and pyridine rings provides a platform for further modification through functional group substitutions or transformations, allowing for the introduction of additional chemical moieties to tune their properties.
In summary, isoquinolines are a class of fused bicyclic organic compounds that are found in natural products and display a wide range of biological activities. They are of considerable importance in medicinal chemistry for drug discovery, as well as in organic synthesis for the construction of complex molecules.
Common Misspellings for ISOQUINOLINES
- usoquinolines
- jsoquinolines
- ksoquinolines
- osoquinolines
- 9soquinolines
- 8soquinolines
- iaoquinolines
- izoquinolines
- ixoquinolines
- idoquinolines
- ieoquinolines
- iwoquinolines
- isiquinolines
- iskquinolines
- islquinolines
- ispquinolines
- is0quinolines
- is9quinolines
- iso1uinolines
- iso2uinolines
Etymology of ISOQUINOLINES
The word "isoquinolines" originates from a combination of two components: "iso" and "quinoline".
- "Iso": In chemistry, the prefix "iso-" is commonly used to suggest the relationship between two similar compounds that are isomers, meaning they have the same molecular formula but differ in the arrangement of atoms. It is derived from the Greek word "ísos", meaning "equal" or "similar".
- "Quinoline": The term "quinoline" refers to a heterocyclic aromatic compound composed of a benzene ring fused to a pyridine ring. The name "quinoline" is derived from the German word "chinolin", which itself was derived from quinine, a natural alkaloid found in the bark of the cinchona tree.
