INTRAVESICAL DRUG ADMINISTRATIONS Meaning and
Definition
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Intravesical drug administration refers to the method of delivering medication or therapeutic agents directly into the urinary bladder through the use of a catheter or other similar medical devices. The term "intravesical" is derived from the Latin words "intra" meaning "inside" and "vesica" meaning "bladder," implying that the drug is administered directly into the bladder.
This mode of drug administration is commonly employed for treating various bladder-related conditions such as urinary tract infections, bladder cancer, interstitial cystitis, and overactive bladder. Intravesical drug administrations aim to deliver the medication directly to the target area of the bladder, providing a localized treatment effect while minimizing systemic distribution and potential side effects.
The drugs used in intravesical therapy can vary depending on the specific condition being treated. These drugs may include antibiotics, anti-inflammatory medications, chemotherapeutic agents, immunosuppressants, or anesthetics. Prior to administration, the bladder is typically emptied to ensure maximum contact between the drug and the bladder wall. The drug is then instilled into the bladder using a catheter, and the patient is instructed to retain the medication for a specific duration before voiding.
Intravesical drug administration offers several advantages, including increased drug concentration in the bladder, reduced systemic exposure, and decreased risk of systemic adverse effects. However, it is essential that this procedure is performed under sterile conditions to prevent potential infections. Close monitoring by healthcare professionals is also necessary to evaluate the patient's response to treatment and manage any potential complications that may arise.
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