INTERACTOME Meaning and
Definition
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Interactome refers to the complete set of molecular interactions that occur within a biological system. It is a comprehensive and dynamic network of various molecules, such as proteins, nucleic acids, and small molecules, as well as the interactions they form with one another. The concept of interactome is derived from the field of systems biology and aims to understand the complex web of relationships between biomolecules.
An interactome can be thought of as a map or blueprint of the molecular machinery that governs the functioning of cells, tissues, and organisms. It provides valuable insights into the intricate interplay between different molecules, their roles, and the effects of their interactions on various biological processes. By unraveling the interactome, scientists can gain a better understanding of the underlying mechanisms involved in diseases, as well as identify potential therapeutic targets.
Interactomes are often studied using high-throughput experimental techniques such as yeast two-hybrid systems, affinity purification coupled with mass spectrometry, and protein microarrays. These methods enable researchers to detect and characterize protein-protein interactions, protein-DNA interactions, protein-RNA interactions, and other molecular associations.
The concept of interactome extends beyond individual organisms to encompass the interactions within entire ecosystems. By studying the interactome of diverse organisms and their environment, scientists can gain insights into ecological relationships, evolutionary processes, and the overall functioning of complex biological systems. Understanding the interactome is crucial for advancing our knowledge of biology and improving human health.
Common Misspellings for INTERACTOME
- unteractome
- jnteractome
- knteractome
- onteractome
- 9nteractome
- 8nteractome
- ibteractome
- imteractome
- ijteractome
- ihteractome
- inreractome
- inferactome
- ingeractome
- inyeractome
- in6eractome
- in5eractome
- intwractome
- intsractome
- intdractome
- intrractome
Etymology of INTERACTOME
The word "interactome" is a combination of two terms: "interact" and "ome".
"Interact" comes from the Latin word "interactare", which means "to act upon one another" or "to have reciprocal influence". It is a combination of the prefix "inter-" meaning "between" and the verb "agere" meaning "to act".
The suffix "-ome" is derived from the Greek word "ōma", which refers to a whole or a complete entity. In biology, it is commonly used to denote the complete set of molecules or genetic material associated with a specific biological system or process. For example, "genome" refers to the complete set of genes in an organism, and "proteome" refers to the complete set of proteins produced by an organism.
Therefore, "interactome" refers to the complete set of molecular interactions that occur within a biological system or organism.
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