INTEGRASE INHIBITORS Meaning and
Definition
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Integrase inhibitors refer to a class of antiretroviral drugs used in the treatment of human immunodeficiency virus (HIV) infection. Specifically, they target and inhibit the action of the viral enzyme called integrase. Integrase is responsible for inserting the viral DNA into the DNA of the host cell, thus facilitating the replication and spread of the virus.
Integrase inhibitors work by binding to and blocking the active site of the integrase enzyme, thereby preventing its function. By doing so, these medications effectively hinder the integration of the viral genetic material into the host cell's genome. This interruption disrupts the replication cycle of the virus and impedes its ability to establish a productive infection.
Due to their mechanism of action, integrase inhibitors are considered a crucial component of combination antiretroviral therapy (cART) for people living with HIV. They are typically prescribed alongside other antiretroviral drugs, targeting different stages of the virus's life cycle, to maximize treatment efficacy and prevent the development of drug resistance.
Integrase inhibitors have demonstrated favorable outcomes in terms of suppressing viral replication, improving immune function, and reducing the viral load in individuals with HIV. They have been found to be generally well tolerated, although some potential side effects may occur, such as headache, gastrointestinal disturbances, or changes in liver function. As with any medication, it is important to adhere to prescribed dosages and follow medical advice when using integrase inhibitors to ensure optimal treatment outcomes.
Common Misspellings for INTEGRASE INHIBITORS
- untegrase inhibitors
- jntegrase inhibitors
- kntegrase inhibitors
- ontegrase inhibitors
- 9ntegrase inhibitors
- 8ntegrase inhibitors
- ibtegrase inhibitors
- imtegrase inhibitors
- ijtegrase inhibitors
- ihtegrase inhibitors
- inregrase inhibitors
- infegrase inhibitors
- ingegrase inhibitors
- inyegrase inhibitors
- in6egrase inhibitors
- in5egrase inhibitors
- intwgrase inhibitors
- intsgrase inhibitors
- intdgrase inhibitors
- intrgrase inhibitors
Etymology of INTEGRASE INHIBITORS
The word "Integrase Inhibitors" has its etymology rooted in Latin and scientific terminology.
1. Integrase: The term "integrase" is derived from Latin. It is composed of two Latin components: "integrum", meaning whole or complete, and "agere", meaning to act or do. In molecular biology, integrases are enzymes that facilitate the integration of viral DNA into the host cell's DNA.
2. Inhibitors: The word "inhibitors" comes from the Latin word "inhibitorem", which means restraining or checking. Inhibitors, in the context of pharmaceuticals, refer to substances or drugs that impede the activity or function of a particular enzyme or protein.
