Indurative nephritis is a medical term used to describe a type of kidney disease where the renal tissue becomes hardened and inflamed. The word is spelled as [ɪnˈdjʊərətɪv nɪˈfraɪtɪs] in IPA phonetic transcription. The "indurative" part of the word is pronounced as "in-dyuh-ruh-tiv" with the emphasis on the second syllable. The "nephritis" part of the word is pronounced as "ne-frahy-tis" with the emphasis on the first syllable. Understanding the phonetic transcription of medical terms can help in correct pronunciation and communication among healthcare professionals.
Indurative nephritis refers to a chronic inflammatory condition that affects the kidneys. It is characterized by the gradual hardening or induration of the renal tissues, leading to impaired kidney function over time. The term "nephritis" specifically refers to inflammation of the kidneys.
Indurative nephritis typically develops as a result of prolonged exposure to certain underlying causes, such as bacterial or viral infections, autoimmune disorders, or chronic drug abuse. The inflammation triggers an immune response within the kidneys, causing the accumulation of scar tissue or fibrosis. This fibrotic tissue restricts the proper functioning of the kidneys, impairing their ability to filter waste products and excess fluids from the bloodstream.
Symptoms of indurative nephritis may vary depending on the severity of the condition and can include fatigue, decreased urine output, high blood pressure, swelling of the legs and ankles, and frequent urinary tract infections. If left untreated, it can progress to advanced stages of kidney disease, which may ultimately lead to kidney failure and the need for dialysis or kidney transplantation.
The diagnosis of indurative nephritis involves thorough medical history evaluation, physical examination, blood tests, urine analysis, and imaging studies like ultrasound or CT scan. Treatment options for this condition aim to manage the underlying causes, alleviate symptoms, and slow down the progression of kidney damage. They may include medications to control blood pressure, reduce inflammation, or manage underlying infections. In severe cases, advanced renal replacement therapies like dialysis or kidney transplantation may be necessary to sustain kidney function.
A chronic inflammation of the kidney characterized by a marked increase of the connective-tissue stroma and atrophy of the secreting portions of the organ.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
The term "indurative nephritis" is a compound made up of two parts: "indurative" and "nephritis".
The word "indurative" is derived from the Latin word "induratus", which means "hardened" or "made hard". It comes from the verb "indure", which means "to make hard or solid". In the context of "indurative nephritis", the term is used to describe a condition in which the renal tissue becomes hardened or fibrotic.
The term "nephritis" is also derived from the Latin language, specifically from the word "nephron", meaning "kidney". The suffix "-itis" denotes inflammation, so "nephritis" refers to inflammation of the kidneys.