Indomethacin hydrochloride is a nonsteroidal anti-inflammatory drug (NSAID) that is commonly used to treat various conditions related to inflammation and pain. It is a derivative of indole-acetic acid and is available as a white crystalline powder.
Indomethacin hydrochloride works by inhibiting the production of certain chemicals in the body that are responsible for causing inflammation and pain. It achieves this by specifically blocking the action of an enzyme called cyclooxygenase (COX), which is involved in the production of prostaglandins. Prostaglandins are chemicals that play a role in several physiological processes, including the initiation of inflammation, fever, and pain.
As an NSAID, indomethacin hydrochloride is prescribed for a variety of conditions, such as rheumatoid arthritis, osteoarthritis, gout, ankylosing spondylitis, and acute painful shoulder. It provides relief by reducing pain, swelling, and joint stiffness associated with these conditions.
Indomethacin hydrochloride is available in various forms, including tablets, capsules, and suppositories. The dosage and frequency of administration depend on the specific condition being treated and the individual patient's response. It is typically taken orally with a full glass of water and may be taken with food or milk to decrease the chance of stomach upset.
However, it is essential to note that indomethacin hydrochloride may cause side effects, including gastrointestinal disturbances, dizziness, headache, and increased blood pressure. It is important to consult a healthcare professional before using this medication to understand its potential risks, interactions, and to ensure its safe and appropriate use.
