The word "indolyl" is spelled with six letters and pronounced as /ˈɪndəʊlɪl/. The word refers to a chemical compound or a functional group containing an indole structure. Indolyl compounds are biologically significant and found in various natural sources. The phonetic transcription of the word follows the International Phonetic Alphabet (IPA) guidelines that represent the sounds of the word more accurately than the traditional English spelling. Understanding the phonetic transcription can aid in proper pronunciation and communication of the chemical concept involved with the word.
Indolyl is an adjective used to describe compounds that contain an indole ring structure. Indole is a heterocyclic organic compound that consists of a six-membered benzene ring fused to a five-membered pyrrole ring. The term "indolyl" is derived from indole, and it signifies that the compound possesses the indole ring system or is a derivative of indole.
Indole rings are known for their diverse biological activities and are found in a wide range of natural products and synthetic compounds. Indolyl compounds have extensive applications in medicinal chemistry, agrochemicals, and material science, owing to their unique chemical properties and versatile reactivity.
The indolyl moiety is often associated with various bioactive compounds and pharmaceutical agents due to its potential for interacting with biological targets. For instance, many natural products containing indolyl structures exhibit interesting pharmacological activities, such as anticancer, antimicrobial, anti-inflammatory, and antiviral properties.
Indolyl derivatives can be synthesized via various synthetic routes, such as indole arylation, indole annulation, or indole condensation reactions. These compounds can be modified further by functional groups substitution on the indole ring, leading to diverse chemical structures with varying properties and activities.
In summary, the term "indolyl" refers to compounds that possess the indole ring system or are derivatives of indole. These compounds have versatile applications in various fields, particularly in medicinal chemistry, due to their unique chemical properties and potential biological activities.
The word "indolyl" is derived from the parent compound "indole".
The term "indole" comes from the German word "indol", which was coined by a German chemist named Adolf von Baeyer in 1866. Baeyer derived the name from the Latin word "indolum", which means "a substance from India".
During Baeyer's time, indole was first isolated from the indigo dye found in plants indigenous to India, specifically Indigofera tinctoria.