Indazole (/ɪnˈdæzɒl/) is a word that is commonly used in organic chemistry to refer to a type of heterocyclic compound. The word is spelled using the letter "I" followed by "n", "d", "a", "z", "o", and "l" in that order. The IPA phonetic transcription of the word highlights the unique sounds in the word, such as the short "i" sound in "in", the "z" sound in "zole", and the "ɒ" sound in "daz". By understanding the correct spelling and pronunciation of indazole, chemists can effectively communicate about this important compound.
Indazole is a heterocyclic compound with a bicyclic structure composed of a benzene ring fused with a pyrazole ring. It belongs to the group of organic compounds known as indazoles. Indazole is a white crystalline solid with a molecular formula C 7 H 6 N 2 .
Indazoles are a class of nitrogen-containing compounds that exhibit diverse biological and pharmacological activities. In recent years, their potential applications as pharmaceuticals and agrochemicals have gained considerable attention due to their wide range of biological properties.
Indazole derivatives have been shown to possess antitumor, antimicrobial, anti-inflammatory, and antiviral activities. These compounds have also exhibited pharmacological properties such as analgesic, antidepressant, and antioxidant effects. Moreover, indazoles have demonstrated promising antifungal and antiparasitic activities against various pathogens.
The synthesis of indazole compounds involves several strategies, including cyclization reactions and annulation processes. Several methods exist for the preparation of indazoles, including metal-catalyzed reactions, thermal reactions, and condensation reactions.
Overall, indazole is a versatile chemical group that plays a vital role in the development of new drugs and agrochemicals. Its unique structure and diverse range of biological activities make it a molecule of significant interest in various fields of research and applications.
The word "indazole" comes from the combination of two components: "ind" and "azole".
1. "Ind" is derived from "indigo", which refers to a deep blue-violet dye historically obtained from the plant Indigofera tinctoria. The term "indigo" is derived from the Greek word "indikon", meaning "Indian dye" or "from India". The plant was predominantly cultivated and the dye was produced in India.
2. "Azole" is a term used to represent a class of organic compounds that contain a five-membered ring with two nitrogen atoms and three carbon atoms. The term "azole" is derived from the fusion of "az-" from "azote", which is an outdated French term for nitrogen, and "-ole" meaning "organic chemical compound" in chemistry.