IMMEDIATE HYPERSENSITIVITY Meaning and
Definition
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Immediate hypersensitivity, also known as type I hypersensitivity or allergic hypersensitivity, is an exaggerated immune response triggered by the exposure to certain allergens. It is a rapid and IgE-mediated reaction that occurs within minutes of contact with the allergen. Immediate hypersensitivity is characterized by the release of histamine and other inflammatory mediators from mast cells and basophils, leading to a plethora of allergic symptoms.
The process begins when an individual who is sensitized to a particular allergen comes into contact with it. This allergen is recognized by the immune system, which then produces specific antibodies known as immunoglobulin E (IgE). These IgE antibodies attach themselves to mast cells and basophils located in various tissues, particularly in the respiratory tract, skin, and gastrointestinal tract.
Upon re-exposure to the same allergen, it binds to the IgE antibodies already attached to the mast cells and basophils. This binding triggers the release of stored mediators, predominantly histamine, from these cells. Histamine then leads to the dilation of blood vessels, increased permeability of capillaries, smooth muscle contraction, and activation of nerve endings.
The allergic symptoms that immediately arise include itching, sneezing, watery eyes, nasal congestion, hives, rashes, swelling, shortness of breath, wheezing, and even anaphylaxis, which is a severe and potentially life-threatening reaction involving the whole body.
Immediate hypersensitivity can be diagnosed through various tests, such as skin prick tests and blood tests to detect specific IgE antibodies. Treatment options may involve the use of antihistamines to relieve symptoms, corticosteroids to control inflammation, and epinephrine in cases of severe reactions. Avoiding exposure to the allergen is key
Common Misspellings for IMMEDIATE HYPERSENSITIVITY
- ummediate hypersensitivity
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- 9mmediate hypersensitivity
- 8mmediate hypersensitivity
- inmediate hypersensitivity
- ikmediate hypersensitivity
- ijmediate hypersensitivity
- imnediate hypersensitivity
- imkediate hypersensitivity
- imjediate hypersensitivity
- immwdiate hypersensitivity
- immsdiate hypersensitivity
- immddiate hypersensitivity
- immrdiate hypersensitivity
- imm4diate hypersensitivity
- imm3diate hypersensitivity
- immesiate hypersensitivity
- immexiate hypersensitivity
Etymology of IMMEDIATE HYPERSENSITIVITY
The etymology of the term "Immediate Hypersensitivity" can be broken down as follows:
1. Immediate: The word "immediate" comes from the Latin word "immediatus", which is derived from the combination of the prefix "im-" (meaning "not") and "medius" (meaning "middle"). Thus, "immediatus" means "not in the middle" or "without anything in between". In the context of immediate hypersensitivity, it refers to the rapid onset of symptoms following exposure to an allergen.
2. Hypersensitivity: The word "hypersensitivity" consists of two parts. The prefix "hyper-" derives from the Greek word "huper" meaning "over" or "excessive". The term "sensitivity" comes from the Latin word "sensibilitas", derived from "sensus" meaning "feeling" or "perception".
