Hypoplastic chondrodystrophy is a rare genetic disorder that affects bone development. The term is composed of three words: hypoplastic, chondro, and dystrophy. The word hypoplastic means underdeveloped, while chondro refers to cartilage and dystrophy means disease. The pronunciation of hypoplastic chondrodystrophy is [haɪpəˈplæstɪk kɒndroʊdɪˈstrɒfi], with emphasis on the second syllable of "plastic" and the first syllable of "chondro." It's important to note that the IPA transcription system helps to accurately represent the sounds of words, making it useful for complex medical terms.
Hypoplastic chondrodystrophy is a medical condition characterized by abnormal development and growth of the cartilage in the body. It is a congenital disorder that affects skeletal development, resulting in dwarfism, disproportionate limb length, and other skeletal abnormalities.
The term "hypoplastic" refers to underdevelopment, while "chondrodystrophy" refers to abnormal growth and development of cartilage. As such, this condition involves a deficiency or incomplete formation of cartilage, which plays a crucial role in the growth and maintenance of bones and other connective tissues.
Individuals with hypoplastic chondrodystrophy typically exhibit short stature and disproportionate limb length, where certain body parts may be disproportionately shorter than others. This condition may also lead to skeletal abnormalities such as shortened limbs, abnormal curvature of the spine, and joint deformities. Other common symptoms include a protruding abdomen, respiratory difficulties, and abnormal facial features.
Hypoplastic chondrodystrophy is usually caused by genetic mutations that affect the production or function of proteins involved in cartilage development. It may be inherited in an autosomal dominant or recessive manner, depending on the specific genetic mutation involved.
Treatment for hypoplastic chondrodystrophy often focuses on managing associated symptoms and complications. This may include physical therapy, orthopedic interventions, or surgical procedures to correct skeletal deformities, improve mobility, and enhance overall quality of life. Genetic counseling may be recommended to help individuals and their families understand the causes, risks, and inheritance patterns associated with this condition.
A form in which the shafts of the long bones are composed of spongy bone with irregular Haversian systems, the marrow cavity is not in the center of the shaft, the ends of the diaphysis are cup-shaped, and the epiphyses are irregular in shape and in time and character of ossification.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
The word "hypoplastic chondrodystrophy" can be broken down into three parts: "hypo", "plastic", and "chondrodystrophy".
1. "Hypo" is a prefix derived from the Greek word "hupó", meaning "under" or "less than normal".
2. "Plastic" is derived from the Greek word "plastikos", meaning "fit for molding or shaping". In medical terms, it is used to describe the ability of tissues or organs to grow, develop, or regenerate.
3. "Chondrodystrophy" is a compound word consisting of "chondro" and "dystrophy". "Chondro" is derived from the Greek word "khondrion", meaning "cartilage".