HYPOPHOSPHATEMIC RICKETS Meaning and
Definition
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Hypophosphatemic rickets is a rare genetic disorder characterized by the impaired absorption and retention of phosphate, a mineral essential for bone health and function. This condition results in the inadequate mineralization of bone tissue, causing weakened and deformed bones.
Individuals with hypophosphatemic rickets typically experience symptoms such as stunted growth, skeletal abnormalities, and bone pain. These symptoms usually manifest during childhood when bones are still growing and developing. However, the severity of symptoms can vary widely, ranging from mild skeletal abnormalities to severe deformities and short stature.
The underlying cause of hypophosphatemic rickets is often a mutation in a gene responsible for regulating phosphate levels in the body, which can be inherited from either one or both parents. This genetic alteration disrupts the normal phosphate reabsorption within the kidneys or the hormonal control of phosphate levels, leading to excessive loss of phosphate through urine or insufficient uptake of phosphate from the intestines.
Treatment for hypophosphatemic rickets typically involves the administration of phosphate and active vitamin D supplements to help restore normal phosphate levels in the body and promote adequate bone mineralization. Regular monitoring of phosphate and calcium levels, as well as periodic imaging of affected bones, is crucial for disease management and assessing treatment efficacy.
Overall, hypophosphatemic rickets is a rare genetic disorder that impairs phosphate metabolism, leading to bone abnormalities and growth retardation. Early diagnosis and appropriate treatment can help alleviate symptoms and improve bone health in affected individuals.
Common Misspellings for HYPOPHOSPHATEMIC RICKETS
- gypophosphatemic rickets
- bypophosphatemic rickets
- nypophosphatemic rickets
- jypophosphatemic rickets
- uypophosphatemic rickets
- yypophosphatemic rickets
- htpophosphatemic rickets
- hgpophosphatemic rickets
- hhpophosphatemic rickets
- hupophosphatemic rickets
- h7pophosphatemic rickets
- h6pophosphatemic rickets
- hyoophosphatemic rickets
- hylophosphatemic rickets
- hy-ophosphatemic rickets
- hy0ophosphatemic rickets
- hypiphosphatemic rickets
- hypkphosphatemic rickets
- hyplphosphatemic rickets
- hyppphosphatemic rickets
Etymology of HYPOPHOSPHATEMIC RICKETS
The word "Hypophosphatemic Rickets" can be broken down into two parts: "hypophosphatemic" and "rickets".
The term "hypophosphatemic" comes from the Greek words "hypo", meaning "under" or "low", and "phosphat(e)", referring to "phosphate". Combined, "hypophosphatemic" implies a condition characterized by low levels of phosphate in the body.
The term "rickets" originates from the Middle English word "riked", meaning "twisted". It was later influenced by the Greek word "rhakhis", meaning "spine". Rickets is a disorder that affects bone development, leading to weak, soft, and deformed bones, often resulting in skeletal deformities.
