The spelling of the word "hurthle cell" can be a challenge for some due to its relatively uncommon usage outside of the medical field. The correct pronunciation of the word is [ˈhɜːrtəl sɛl], with the "h" being silent and "e" being pronounced as "uh". The "th" sound in "hurthle" is represented by the letter "t" followed by the letter "h". The word refers to a type of cell found in the thyroid gland, and correctly spelling it is important for accurate diagnoses and treatment plans.
A "hurthle cell" is a term used in the medical field to describe a specific type of cell found in the thyroid gland. This type of cell is characterized by its distinct appearance under a microscope, as it has a large, granular, and eosinophilic cytoplasm (the material that fills the cell) with a centrally located nucleus.
The presence of hurthle cells in the thyroid gland can be indicative of various conditions, with the most common being a Hurthle cell adenoma or a Hurthle cell carcinoma. A Hurthle cell adenoma is a non-cancerous growth of hurthle cells in the thyroid, while a Hurthle cell carcinoma is a malignant or cancerous growth of hurthle cells. These conditions can cause enlargement of the thyroid gland or result in an overproduction of thyroid hormones, leading to symptoms such as weight changes, fatigue, and changes in heart rate.
Diagnosing the presence of hurthle cells involves microscopic examination of a tissue sample obtained through a fine-needle aspiration biopsy or surgical removal of the thyroid. Identification of hurthle cells helps clinicians determine the appropriate treatment plan, which may involve surgery, radioactive iodine therapy, or hormone replacement therapy.
Overall, the term "hurthle cell" refers to a specific type of cell found in the thyroid gland, with its presence playing a crucial role in diagnosing and managing various thyroid conditions.
The term "hurthle cell" originated from a pathologist named Karl Wilhelm Hurthle. He was a German physician who worked in the late 19th and early 20th centuries. Hurthle cells are large, granular cells that can be found in the thyroid gland. They are named after Hurthle due to his contribution to the understanding and identification of these cells in thyroid pathology.