HOMODIMER Meaning and
Definition
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A homodimer is a protein structure consisting of two identical subunits or monomers that are connected together. It is commonly found in biological molecules, particularly enzymes and receptors. The term "homo" refers to the similarity or sameness of the subunits, indicating that both subunits have the exact same amino acid sequence and structural arrangement.
Homodimers are formed through noncovalent interactions between the subunits, such as hydrogen bonds, hydrophobic interactions, and electrostatic forces. These interactions stabilize the structure and enable the two subunits to bind to each other. The binding interface between the subunits is often highly specific, allowing for precise recognition and formation of the homodimer.
In a homodimer, each subunit typically retains similar functions as an individual monomer, and the function of the homodimer is often a result of the combined activity of both subunits. The binding and reaction sites of a homodimer are frequently located at the interfaces of the subunits, where the subunits may work cooperatively to enhance catalytic efficiency or influence signal transmission.
Homodimers play an essential role in various biological processes, including signal transduction, gene regulation, and enzymatic activities. They can function as enzymes, receptors, transcription factors, or structural components, among others. Understanding the structure and function of homodimers is crucial for deciphering various biological mechanisms and designing therapeutics that can target and modulate their activities.
Common Misspellings for HOMODIMER
- gomodimer
- bomodimer
- nomodimer
- jomodimer
- uomodimer
- yomodimer
- himodimer
- hkmodimer
- hlmodimer
- hpmodimer
- h0modimer
- h9modimer
- honodimer
- hokodimer
- hojodimer
- homidimer
- homkdimer
- homldimer
- hompdimer
- hom0dimer
Etymology of HOMODIMER
The word "homodimer" is formed by combining two separate parts: "homo-" and "-dimer".
The prefix "homo-" is derived from the Greek word "homós", meaning "same" or "alike". It is commonly used in scientific terminology to denote something that is similar or identical.
The suffix "-dimer" comes from the Greek word "dímeros", which means "two parts" or "two units". In scientific terms, it is used to describe a molecule or complex made up of two identical subunits.
Therefore, when combined, the word "homodimer" refers to a complex composed of two identical subunits or molecules.
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