HOBO TRANSPOSASE Meaning and
Definition
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The term "Hobo transposase" refers to a specific type of transposase enzyme called Hobo that is typically found in certain strains of the fruit fly Drosophila melanogaster. Transposase enzymes are responsible for catalyzing the movement of transposable elements, or transposons, within the genome. Transposons are genetic sequences that have the ability to change their position within the genome, which can have significant impacts on gene expression and genome evolution.
The Hobo transposase, named after its discovery in the genome of Drosophila melanogaster, is a member of the hAT (hobo, Activator, Tam3) family of transposases. The hAT family is one of the most abundant and diverse families of transposases found across a wide range of organisms. It is characterized by the presence of a specific DNA-binding domain called the DDE motif, which plays a crucial role in the recognition and cleavage of DNA during transposition.
Hobo transposase is known for its ability to recognize specific DNA sequences known as inverted terminal repeats (ITRs) present at the ends of transposons. These ITRs are bound by the transposase, which then mediates the excision and reintegration of the transposon into new genomic locations. The movement of these transposons through the actions of Hobo transposase can result in genetic rearrangements, insertions, or deletions within the host genome.
Overall, the Hobo transposase is a key player in the process of transposition, allowing for the dynamic reshuffling of genetic material within genomes, which can contribute to genetic diversity and evolution in various organisms.
Common Misspellings for HOBO TRANSPOSASE
- gobo transposase
- bobo transposase
- nobo transposase
- jobo transposase
- uobo transposase
- yobo transposase
- hibo transposase
- hkbo transposase
- hlbo transposase
- hpbo transposase
- h0bo transposase
- h9bo transposase
- hovo transposase
- hono transposase
- hoho transposase
- hogo transposase
- hobi transposase
- hobk transposase
- hobl transposase
- hobp transposase
Etymology of HOBO TRANSPOSASE
The word "Hobo transposase" is derived from two elements: "Hobo" and "transposase".
1. Hobo: The term "Hobo" is derived from the "hobo" transposable element that was discovered in 1983 in the fruit fly (Drosophila melanogaster). This transposable element was named after the itinerant American workers known as "hobos" due to its ability to move around the genome in a seemingly random manner.
2. Transposase: "Transposase" is a general term used to describe the enzyme responsible for the movement of transposable elements within an organism's genome. It facilitates the excision of transposons (segments of DNA that can move from one location to another within a genome) and their insertion into new locations.
