How Do You Spell HIV INTEGRASE INHIBITORS?

Pronunciation: [ˌe͡ɪt͡ʃˌa͡ɪvˈiː ˈɪntɪɡɹˌe͡ɪz ɪnhˈɪbɪtəz] (IPA)

HIV Integrase Inhibitors are a class of antiretroviral drugs used to treat HIV infections. The word "integrase" is spelled /ˈɪntəɡreɪs/ with the stress on the second syllable. "Inhibitors" is spelled /ɪnˈhɪbɪtərz/, with the stress on the second syllable. HIV Integrase Inhibitors work by blocking the HIV integrase enzyme, which is responsible for incorporating viral DNA into the host cell's genome. This prevents the virus from replicating and can help to slow or stop the progression of HIV/AIDS.

HIV INTEGRASE INHIBITORS Meaning and Definition

1. HIV Integrase Inhibitors are a class of antiretroviral drugs used in the treatment of human immunodeficiency virus (HIV) infection. These inhibitors specifically target and inhibit the action of the viral enzyme called integrase, which plays a crucial role in the replication and integration of the HIV genome into the host cell's DNA.

   Integrase is responsible for catalyzing the process of integration, where the viral DNA is integrated into the DNA of the host cell, enabling the virus to replicate and persist within the human body. By blocking the activity of integrase, HIV Integrase Inhibitors prevent the integration of viral DNA, disrupting viral replication and reducing the viral load in affected individuals.

   These inhibitors are typically used in combination with other antiretroviral drugs as part of highly active antiretroviral therapy (HAART) to achieve optimal suppression of HIV replication. HIV Integrase Inhibitors are available in oral form and are usually taken once or twice daily.

   Commonly used HIV Integrase Inhibitors include raltegravir, elvitegravir, dolutegravir, and bictegravir. These drugs have shown high efficacy in suppressing viral replication and have been associated with significant improvements in immune function and reductions in morbidity and mortality among HIV-infected individuals.

   While generally well-tolerated, these inhibitors may have some side effects, including gastrointestinal disturbances, headaches, and abnormal liver function. Therefore, individuals taking HIV Integrase Inhibitors should be monitored regularly for any potential adverse effects.

Common Misspellings for HIV INTEGRASE INHIBITORS

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