How Do You Spell HISTONE LYSINE N METHYLTRANSFERASE?

Pronunciation: [hˈɪstə͡ʊn lˈa͡ɪsa͡ɪn ˈɛn mˈiːθɪltɹɐnsfˌɜːɹe͡ɪz] (IPA)

The word "Histone Lysine N Methyltransferase" is a mouthful to pronounce, as it contains multiple consonants and vowels. Using the IPA phonetic transcription, it can be broken down as "hɪstoʊn laɪsiːn ɛn mɛθəltrænsfeɪs". This transcription helps to explain how each syllable should be pronounced, emphasizing the stress on each syllable. This word refers to an enzyme that performs a crucial role in the regulation of gene expression. Despite its challenging spelling, "Histone Lysine N Methyltransferase" plays a critical role within the biological field.

Meaning and Definition
Common Misspellings
Basic Check Advanced Check

HISTONE LYSINE N METHYLTRANSFERASE Meaning and Definition

  1. Histone Lysine N Methyltransferase is an enzyme that plays a crucial role in the process of DNA packaging and gene regulation, particularly in eukaryotic organisms. It belongs to the family of methyltransferases, which are responsible for adding methyl groups to various target molecules.

    Specifically, histone lysine N methyltransferases (HKMTs) catalyze the transfer of a methyl group (-CH3) from the cofactor S-adenosylmethionine (SAM) to the amino acid lysine present in the tails of histone proteins. Histone proteins are responsible for packaging and organizing DNA into a condensed structure called chromatin, which directly affects gene expression.

    The addition of methyl marks by histone lysine N methyltransferases to specific lysine residues on histones can have profound effects on gene activity. Methylation of histones can either activate or repress gene expression, depending on the specific target site and the context of other histone modifications. In this way, histone lysine N methyltransferases contribute to the epigenetic control of gene regulation, allowing cells to maintain a stable gene expression pattern.

    Dysregulation or mutations in histone lysine N methyltransferases have been associated with various diseases, including cancer, neurodevelopmental disorders, and immune dysfunctions. Therefore, understanding the function and mechanism of histone lysine N methyltransferases is critical for unraveling the complex processes of gene regulation and potentially developing therapeutic interventions for various diseases.

Common Misspellings for HISTONE LYSINE N METHYLTRANSFERASE

  • gistone lysine n methyltransferase
  • bistone lysine n methyltransferase
  • nistone lysine n methyltransferase
  • jistone lysine n methyltransferase
  • uistone lysine n methyltransferase
  • yistone lysine n methyltransferase
  • hustone lysine n methyltransferase
  • hjstone lysine n methyltransferase
  • hkstone lysine n methyltransferase
  • hostone lysine n methyltransferase
  • h9stone lysine n methyltransferase
  • h8stone lysine n methyltransferase
  • hiatone lysine n methyltransferase
  • hiztone lysine n methyltransferase
  • hixtone lysine n methyltransferase
  • hidtone lysine n methyltransferase
  • hietone lysine n methyltransferase
  • hiwtone lysine n methyltransferase
  • hisrone lysine n methyltransferase
  • hisfone lysine n methyltransferase