HIGH MANNOSE Meaning and
Definition
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High Mannose refers to a type of glycan structure commonly found in the carbohydrates present on the outer surface of glycoproteins. Glycoproteins are proteins that are covalently bonded to carbohydrates, and these carbohydrates play significant roles in their structure and function. The high mannose type glycan structure is characterized by the presence of a large number of mannose sugar residues.
Specifically, high mannose glycan structures are composed of a central core of mannose sugars, which may be further branched. These structures can vary in size and composition, typically covering a range of 5 to 25 mannose residues. The presence of high mannose glycan structures on glycoproteins has implications for their biological and structural functions.
High mannose structures are involved in various cellular processes, including protein folding, sorting, and recognition. They mediate interactions with receptors and other proteins, modulating cell signaling, immune responses, and host-pathogen interactions. Furthermore, high mannose glycan structures have been associated with certain disease states, such as congenital disorders of glycosylation and viral infections.
Understanding the role of high mannose structures is crucial for deciphering the functions of glycoproteins and their role in various biological processes. Ongoing research aims to unravel the intricacies of high mannose glycan structures, enabling advancements in fields such as immunology, virology, and drug development.
Common Misspellings for HIGH MANNOSE
- gigh mannose
- bigh mannose
- nigh mannose
- jigh mannose
- uigh mannose
- yigh mannose
- hugh mannose
- hjgh mannose
- hkgh mannose
- hogh mannose
- h9gh mannose
- h8gh mannose
- hifh mannose
- hivh mannose
- hibh mannose
- hihh mannose
- hiyh mannose
- hith mannose
- higg mannose
- higb mannose
