HGF RECEPTOR Meaning and
Definition
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The HGF receptor, also known as the hepatocyte growth factor receptor or c-Met receptor, is a transmembrane protein present on the surface of cells. It belongs to the receptor tyrosine kinase family and plays a crucial role in various cellular processes, particularly cell growth, development, and tissue regeneration.
The HGF receptor is primarily activated by binding with its ligand, hepatocyte growth factor (HGF), also referred to as scatter factor. Upon ligand binding, the receptor undergoes a conformational change, resulting in the activation of its intracellular tyrosine kinase domain. This activation triggers a series of molecular events and biochemical signaling pathways that regulate cellular proliferation, motility, and morphogenesis.
Abnormal activation or dysregulation of the HGF receptor can be associated with numerous pathological conditions, including cancer, metastasis, and tissue fibrosis. Overexpression of the receptor or aberrant signaling can promote uncontrolled cell growth, invasion, and metastasis, contributing to tumorigenesis. Consequently, the HGF receptor has become an attractive target for therapeutic interventions, and the development of inhibitors that can selectively block its activity is an active area of research.
Overall, the HGF receptor plays a vital role in mediating cell responses to the extracellular environment, orchestrating cellular processes critical for development, tissue repair, and disease progression. Understanding its function and regulation may provide valuable insights for the development of novel therapies and treatment strategies in various pathological conditions.
Common Misspellings for HGF RECEPTOR
- jgf receptor
- ygf receptor
- hff receptor
- hvf receptor
- hbf receptor
- hhf receptor
- hyf receptor
- htf receptor
- hgd receptor
- hgv receptor
- hgt receptor
- hgr receptor
- hgf eeceptor
- hgf deceptor
- hgf feceptor
- hgf teceptor
- hgf 5eceptor
- hgf 4eceptor
- hgf rwceptor
- hgf rsceptor
Etymology of HGF RECEPTOR
The etymology of the word "HGF receptor" can be understood by breaking it down into its constituent parts.
1. HGF: The acronym "HGF" stands for Hepatocyte Growth Factor. It is a protein that plays a crucial role in cell growth, proliferation, and differentiation.
2. Receptor: The term "receptor" refers to a molecule or a structure found on the surface of a cell. It has the ability to bind to specific molecules, such as growth factors or hormones, and initiate cellular responses.
Therefore, the etymology of "HGF receptor" is derived from the name of the growth factor it interacts with (HGF) and the term "receptor", indicating its role in binding and mediating the effects of HGF on cells.
