HETEROTRIMER Meaning and
Definition
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A heterotrimer is a molecular complex consisting of three different subunits that are non-identical in structure. The term is commonly used in biochemistry and molecular biology to refer to protein complexes in which all three subunits have distinct amino acid sequences and functions. These complexes play crucial roles in various cellular processes.
Heterotrimers are typically composed of two similar subunits and one distinct subunit, forming a trimeric structure. The interactions between these subunits are essential for the stability and function of the heterotrimeric complex. Each subunit contributes to the overall function of the complex, often by performing specific tasks or fulfilling distinct roles within a cellular pathway.
Heterotrimers are involved in numerous physiological processes, such as signal transduction, cell adhesion, and enzymatic reactions. For example, G-proteins, a class of heterotrimers, are essential components of cell signaling pathways, coordinating various cellular responses. Another example is the heterotrimeric GABA receptor, which mediates inhibitory neurotransmission in the brain.
The study of heterotrimers is important for understanding the molecular mechanisms underlying cellular functions and developing therapeutic strategies for diseases associated with dysfunctional protein complexes. By elucidating the structures and functions of heterotrimers, researchers can unravel the complexities of cellular networks and identify potential targets for drug development.
Common Misspellings for HETEROTRIMER
- geterotrimer
- beterotrimer
- neterotrimer
- jeterotrimer
- ueterotrimer
- yeterotrimer
- hwterotrimer
- hsterotrimer
- hdterotrimer
- hrterotrimer
- h4terotrimer
- h3terotrimer
- hererotrimer
- heferotrimer
- hegerotrimer
- heyerotrimer
- he6erotrimer
- he5erotrimer
- hetwrotrimer
- hetsrotrimer
Etymology of HETEROTRIMER
The word "heterotrimer" is derived from the combination of two elements: "hetero-" and "trimer".
1. "Hetero-" is a prefix derived from the Greek word "heteros", meaning "different" or "other". It is often used in scientific and technical terms to indicate variations or differences from the norm. In the case of "heterotrimer", it suggests that the trimer in question is composed of different or varied subunits.
2. "Trimer" is a noun derived from the Greek word "tris", meaning "three". It refers to a molecule, compound, or structure composed of three similar subunits or components.
Therefore, combining these two elements, the term "heterotrimer" specifically refers to a trimeric structure composed of different or varied subunits.
