The word "Hetastarch" is spelled phonetically as /ˈhiːtəstɑːrk/. This word consists of two morphemes: "heta" meaning "heat" and "starch" meaning "a carbohydrate consisting of a large number of glucose units". The spelling of "Hetastarch" reflects the standard English pronunciation of its two constituent morphemes. The prefix "heta" is pronounced as /ˈhiːtə/ with a long vowel sound in the first syllable, and "starch" is pronounced as /stɑːrk/ with a short "a" sound in the first syllable.
Hetastarch is a synthetic colloid solution derived from starch, often used for intravenous administration to treat or prevent hypovolemia, which is the condition of low blood volume. It is chemically modified in order to create a stable suspension that can be administered intravenously to rapidly increase blood volume. Hetastarch is used as a plasma expander because it is capable of expanding blood plasma and increasing the overall volume of circulating blood within a short period of time.
Hetastarch works by exhibiting oncotic pressure, which means it pulls fluids into the blood vessels and keeps them within the circulatory system. This function serves to maintain proper blood volume and thus, blood pressure. It has the capability to draw fluid from the interstitial spaces, where fluids accumulate during hypovolemia or dehydration, and move it back into the blood vessels. Therefore, it can help restore blood flow to vital organs and tissues.
It is important to note that hetastarch is typically used when crystalloid solutions like normal saline or lactated Ringer's solution are inadequate to restore blood volume. It is commonly used during surgical procedures, trauma cases, and in critically ill patients. However, it should be administered with caution and with constant monitoring for adverse effects, as it may be associated with complications such as coagulopathy, renal impairment, and allergic reactions.
The word "Hetastarch" is a combination of two parts: "heta" and "starch".
The term "heta" is derived from "hydroxyethyl", which refers to the chemical compound hydroxyethyl starch (HES). HES is a type of starch that has been modified through the addition of hydroxyethyl groups. These modifications enhance its solubility and reduce its degradation by enzymes.
The word "starch" originates from the Old English word "stærċ", which means stiff or rigid. It refers to the polysaccharide carbohydrate found in various plants, used by them as an energy storage molecule. Starch consists of glucose units linked together, forming a chain-like structure.
When combined, "heta" and "starch" describe a specific type of starch that has been chemically modified by the addition of hydroxyethyl groups.