HEPARIN Meaning and
Definition
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Heparin is a noun that refers to a naturally occurring substance that is found in the liver, lungs, and other tissues of mammals. It is a highly sulfate glycosaminoglycan, which means it is a long, linear polysaccharide consisting of repeating disaccharide units and is composed of alternating residues of D-glucosamine and D-glucuronic acid. Heparin is known for its anticoagulant properties and is widely used as a medication to prevent the formation of blood clots in the body.
Heparin works by inhibiting the activity of certain clotting factors in the blood, such as thrombin and factor Xa, which are responsible for promoting blood clot formation. By doing so, heparin helps to prevent the formation of new clots and also prevents existing clots from getting larger. This makes it an effective medication in the treatment and prevention of conditions such as deep vein thrombosis, pulmonary embolism, and various cardiovascular disorders where blood clotting poses a risk.
Heparin can be administered either intravenously or subcutaneously, depending on the specific condition being treated. It is typically used in hospitals or healthcare settings and is available in different forms, including unfractionated heparin and low molecular weight heparin. The dosage and frequency of administration are determined by medical professionals based on individual patient factors such as body weight, medical history, and the specific condition being treated.
It is important to note that heparin, like any medication, can have potential side effects and should be used under the supervision of qualified healthcare professionals.
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Etymology of HEPARIN
The term "heparin" comes from the Greek word "hepar", meaning "liver". It was named so because it was first discovered and isolated in 1916 by Jay McLean, a medical researcher, from the liver tissues of dogs. Initially, heparin was presumed to be a component of the liver, but later it was found to be present in larger amounts in other tissues like mast cells and lungs as well. Heparin is a naturally occurring anticoagulant, which prevents blood clotting, and is commonly used in medical settings for various purposes.
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