HEMOPHILIA A Meaning and
Definition
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Hemophilia A is a hereditary bleeding disorder characterized by the deficiency or absence of clotting factor VIII (FVIII), a protein essential for blood clotting. It is the most common and severe form of hemophilia, affecting predominantly males, although rare cases in females have also been reported.
Individuals with hemophilia A have impaired blood clotting, which can lead to excessive bleeding, both internally and externally. Even minor injuries can cause prolonged bleeding episodes, and spontaneous bleeding into joints, muscles, and organs can occur without apparent cause. Common symptoms of hemophilia A include easy bruising, prolonged bleeding after injuries or surgeries, and spontaneous joint or muscle bleeds that lead to pain and limited movement.
Hemophilia A is an X-linked recessive genetic disorder, meaning that the defective gene responsible for the condition is located on the X chromosome. As a result, males are primarily affected, while females usually act as carriers, passing down the mutated gene to their offspring. However, in rare cases, females can experience mild symptoms if they inherit the gene from both parents.
Treatment for hemophilia A aims at replacing the missing blood clotting factor VIII. Recombinant FVIII concentrates or plasma-derived FVIII are administered intravenously to control bleeding episodes and prevent complications. Regular prophylactic treatment may be recommended to maintain adequate levels of clotting factors and minimize the risk of spontaneous bleeding. With proper management, individuals with hemophilia A can lead normal lives and reduce the impact of the disorder on their daily activities.
Common Misspellings for HEMOPHILIA A
- gemophilia a
- bemophilia a
- nemophilia a
- jemophilia a
- uemophilia a
- yemophilia a
- hwmophilia a
- hsmophilia a
- hdmophilia a
- hrmophilia a
- h4mophilia a
- h3mophilia a
- henophilia a
- hekophilia a
- hejophilia a
- hemiphilia a
- hemkphilia a
- hemlphilia a
- hempphilia a
Etymology of HEMOPHILIA A
The word "hemophilia" is derived from the Greek words "haima" meaning "blood" and "philos" meaning "loving". It was first coined by the German physician Friedrich Hopff in 1828 to describe a hereditary bleeding disorder characterized by prolonged bleeding due to the inability of blood to clot properly. The term "hemophilia A" specifically refers to the most common form of hemophilia, which results from a deficiency or dysfunction of clotting factor VIII.
Similar spelling words for HEMOPHILIA A
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