H SUBSTANCE Meaning and
Definition
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H substance refers to a blood group antigen that determines the presence of the H antigen on the surface of red blood cells. The H antigen is a precursor to the A and B antigens, which further determine an individual's blood type. This substance is crucial in determining the compatibility of blood for transfusion purposes and plays a significant role in transfusion medicine.
The H substance is a carbohydrate structure that acts as the backbone for the A and B antigens. It anchors these antigens to the red blood cell surface, helping in the recognition and interaction with antibodies found in the blood plasma. The presence of the H substance is necessary for the development of A and B antigens, while its absence leads to the blood type O, where no A or B antigens are present on the surface of red blood cells.
The H substance is produced by enzymes called fucosyltransferases that add the fucose sugar molecule to a precursor substance. Variations in the genetic code can affect the production of these enzymes, leading to different blood types. The presence or absence of the H substance on red blood cells can determine the compatibility of blood for transfusion, as individuals lacking the H antigen may produce antibodies against it and potentially cause a transfusion reaction.
In conclusion, the H substance is an essential blood group antigen that determines the presence of the H antigen on red blood cells. Its presence or absence has significant implications for the development of A and B antigens, blood type determination, and blood transfusion compatibility.
Common Misspellings for H SUBSTANCE
- g substance
- b substance
- n substance
- j substance
- u substance
- y substance
- h aubstance
- h zubstance
- h xubstance
- h dubstance
- h eubstance
- h wubstance
- h sybstance
- h shbstance
- h sjbstance
- h sibstance
- h s8bstance
- h s7bstance
- h suvstance
- h sunstance
