GUANOSINE DIPHOSPHOMANNOSE Meaning and
Definition
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Guanosine diphosphomannose (GDP-mannose) is a biologically significant nucleotide derivative that plays a crucial role in various biochemical processes. It is composed of a guanosine molecule, which consists of the nitrogenous base guanine linked to the sugar ribose, and two phosphate groups attached to the ribose sugar.
GDP-mannose is an essential precursor molecule required for the synthesis of complex carbohydrates, particularly in glycosylation reactions. Glycosylation involves the attachment of sugar molecules to proteins and lipids, thereby modifying their structure and function.
In cells, GDP-mannose acts as a donor of mannose residues for the biosynthesis of a variety of glycoconjugates, including glycoproteins, glycolipids, and polysaccharides. It serves as a substrate for various enzymes involved in glycosylation reactions, transferring the mannose moiety onto an acceptor molecule.
Additionally, GDP-mannose participates in the biosynthesis of extracellular polysaccharides, such as the polysaccharide capsule of certain bacteria. These capsules act as a protective coating against host immune responses, contributing to bacterial virulence.
Overall, the availability of GDP-mannose is crucial for the proper functioning of various cellular processes and the maintenance of glycosylation pathways. Its presence enables the cell to constantly modulate and diversify its glycoconjugates, which are essential for numerous biological functions, including cell adhesion, signaling, and immune responses.
Common Misspellings for GUANOSINE DIPHOSPHOMANNOSE
- fuanosine diphosphomannose
- vuanosine diphosphomannose
- buanosine diphosphomannose
- huanosine diphosphomannose
- yuanosine diphosphomannose
- tuanosine diphosphomannose
- gyanosine diphosphomannose
- ghanosine diphosphomannose
- gjanosine diphosphomannose
- gianosine diphosphomannose
- g8anosine diphosphomannose
- g7anosine diphosphomannose
- guznosine diphosphomannose
- gusnosine diphosphomannose
- guwnosine diphosphomannose
- guqnosine diphosphomannose
- guabosine diphosphomannose
- guamosine diphosphomannose
- guajosine diphosphomannose
- guahosine diphosphomannose
Etymology of GUANOSINE DIPHOSPHOMANNOSE
The word "Guanosine Diphosphomannose" is a scientific term used in biochemistry and molecular biology. It is composed of several parts:
1. Guanosine: The term "guanosine" derives from the base "guanine", which is one of the four nucleotide bases (along with adenine, cytosine, and thymine) found in DNA and RNA. Guanosine is a nucleoside, which means it consists of a sugar molecule (ribose) bonded to the base guanine.
2. Diphospho: The term "diphospho" indicates the presence of two phosphate groups. In this case, it signifies that two phosphate groups are attached to the guanosine molecule.
3. Mannose: Mannose is a sugar molecule, specifically a monosaccharide.
