GUANINE AMINOHYDROLASE Meaning and
Definition
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Guanine aminohydrolase is an enzyme found in living organisms that plays a vital role in the metabolism of guanine, one of the four nucleotide bases present in DNA and RNA. This enzyme, also known as guanine deaminase, acts on guanine molecules by catalyzing a reaction that removes the amino group attached to the guanine molecule. The process of removing the amino group from guanine results in its conversion to xanthine, which is then further metabolized into uric acid.
Guanine aminohydrolase is commonly found in various species, including bacteria, plants, and animals, and it is particularly important in the purine salvage pathway. In this pathway, the enzyme aids in the recycling of guanine by converting it into a form that can be reused in the synthesis of nucleic acids.
The activity of guanine aminohydrolase is tightly regulated within the cell to maintain the proper balance of nucleotides. Any disturbances in the regulation of this enzyme can lead to imbalances in nucleotide levels and affect important cellular processes, such as DNA replication and protein synthesis. Deficiencies in guanine aminohydrolase activity have also been linked to certain metabolic disorders, such as Lesch-Nyhan syndrome, which is characterized by a buildup of uric acid and neurological abnormalities.
Overall, guanine aminohydrolase plays a crucial role in the metabolism of guanine, ensuring the proper balance of nucleotides in the cell and contributing to the overall functioning of living organisms.
Common Misspellings for GUANINE AMINOHYDROLASE
- fuanine aminohydrolase
- vuanine aminohydrolase
- buanine aminohydrolase
- huanine aminohydrolase
- yuanine aminohydrolase
- tuanine aminohydrolase
- gyanine aminohydrolase
- ghanine aminohydrolase
- gjanine aminohydrolase
- gianine aminohydrolase
- g8anine aminohydrolase
- g7anine aminohydrolase
- guznine aminohydrolase
- gusnine aminohydrolase
- guwnine aminohydrolase
- guqnine aminohydrolase
- guabine aminohydrolase
- guamine aminohydrolase
- guajine aminohydrolase
- guahine aminohydrolase
Etymology of GUANINE AMINOHYDROLASE
The etymology of the word "Guanine Aminohydrolase" can be broken down as follows:
1. Guanine: The term "guanine" originates from the word "guano", which refers to bird droppings. Guanine was first isolated from guano by the physician and chemist Julius Bodo Unger in 1844. Guanine is one of the four nucleobases that form the building blocks of DNA and RNA.
2. Amino: The word "amino" comes from the French word "amine", which was derived from the Latin "ammonia", referring to a pungent gas obtained from the putrid fermentation of urine. In the context of biochemistry, "amino" relates to substances or compounds containing an amino group (-NH2), which is a crucial component of proteins and various other organic molecules.
